HBC June-July 2019 News Bulletin

Wednesday, July 31, 2019

 

HBC Interim Director

John StobaughBill Picking stepped down from his position as director of the Higuchi Biosciences Center (HBC) at the end of June 2019 to focus on his research and teaching commitment.  As of July 1st, John Stobaugh assumed the role of interim director of HBC.  He is a professor of pharmaceutical chemistry and associate dean of research & graduate affairs in the School of Pharmacy.  He also serves as associate director of academic research at the HBC.

We would like to take this opportunity to thank Bill Picking for his service as director of the HBC for these past five years.

 

O’Leary Shared Service Center Satellite Office

This is a reminder that on July 17, 2019 the O’Leary Shared Service Center began to hold office hours in KU’s West District to facilitate in-person meetings for PI’s located in the district.  The satellite office is located in McCollum Laboratories, Room 129.  It is open the 1st and 3rd Wednesday of the month from 1 to 4 pm. 

 

Upcoming Fall Symposium

GRASP logoThe An HBC sponsored symposium is scheduled for this coming fall.   The 2019 Great Plains Regional Annual Symposium on Protein and Biomolecular NMR (GRASP NMR), a regional symposium on macromolecular NMR applications and techniques, will be held at the KU School of Pharmacy building on November 22 -23, 2019.  Registration is currently open and early-bird registration fees will be available until September 10, 2019.           

 

J.R. & Inez Jay Fund Research Awards   

Adam SmithMark Farrell

Two projects were selected this year to receive the 2019 J.R. and Inez Jay Fund research award at the University of Kansas. The first proposal selected, titled “Sugar coated vaccines for the treatment of opioid use disorder,” was submitted by Mark Farrell, assistant professor of medicinal chemistry, and Adam Smith, assistant professor of pharmacology and toxicology. The project will investigate a new approach to opioid conjugate vaccines.

Mark RichterThe second project selected was submitted by Mark Richter, professor of molecular biosciences.   The project, titled “Continuous monitoring of histamine in the brain,” will be conducted in collaboration with Candan Tamerler, professor of mechanical engineering, Paul Hanson, professor of chemistry, and George Wilson, distinguished professor emeritus of chemistry.   The proposal addresses the need for real-time continuous measurement of histamine levels in the brain and in other tissues as a biomarker and pre-indicator of multiple immunological, neurological, and cardiovascular disorders.

 

KU NIH Center of Biomedical Research Excellence (CoBRE) in Chemical Biology of Infectious Disease (CBID) Pilot Projects awards

The KU NIH CoBRE in Chemical Biology of Infectious Disease (CBID) received sixteen innovative and well qualified Pilot Project applications in February.  Out of the six selected proposals (four potential awards and two alternates) sent to NIH, four projects were approved.  They are:

  • Dr. Brian Ackley – University of Kansas, “On again, off again: Is pH a critical factor in pathogen killing?”
  • Dr. Josie Chandler – University of Kansas, “Chemical biology studies of malleilactone, a small-molecule toxin produced by Burkholderia pseudomallei”
  • Dr. Philip Hardwidge – Kansas State University, “Bacterial glycosyltransferase inhibitors as anti-virulence compounds”
  • Dr. Wolfram Zückert – University of Kansas Medical Center, “Small molecule inhibitors of bacterial surface lipoprotein secretion”

Congratulations to all.



HBC Events
Grant Submission Deadlines

October 3, 2019
NIH deadline for the Maximizing Investigators' Research Award (R35) for Early Stage Investigators.

October 5, 2019
NIH standard deadline for Research Grants and Cooperative Agreements (R01 and U01) – new submissions.

October 8-22, 2019
American Heart Association (AHA) awards submission deadlines for:

October 12, 2019
NIH standard deadline for Research Career Development (K series) – new submissions.

October 16, 2019
NIH standard deadline for Other Research Grants and Cooperative Agreements (R03, R21, R33, R21/R33, R34, R36, UH2, UH3, UH2/UH3) – new submissions.

Recent Awards

Christopher Fischer, Associate Professor, Department of Physics and Astronomy, was awarded $147,450 by the American Physics Society for his project entitled: “PhysTEC Comprehensive Site.”

Mei He, Assistant Professor, Departments of Chemical & Petroleum Engineering and Chemistry, was awarded $1,893,750 by the National Institutes of Health, for her project entitled: “3D biomimetic lymph node engineered extracellular vesicles for understanding the heterogeneity of adaptive immunity.”

Stuart Macdonald, Professor, Department of Molecular Biosciences, was awarded $159,075 by KU Medical Center for his project entitled: “KINBRE Bioinformatics Core Facility.”

Frank Schoenen, Associate Research Professor, Higuchi Biosciences Center, was awarded $553,962 by Kansas State University for his project entitled: “Discovery of Hsp100-selective inhibitors for targeting multiple microbial pathogens.”

Robert Ward, Associate Professor, Department of Molecular Biosciences, was awarded a total of $125,745 by the KU Medical Center for four KINBRE projects: “Summer Scholars”, “Campus Coordinator”, “Star Trainees” and “Undergraduate Coordinator Office.”

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