HBC June-July 2019 News Bulletin

Wednesday, July 31, 2019

 

HBC Interim Director

John StobaughBill Picking stepped down from his position as director of the Higuchi Biosciences Center (HBC) at the end of June 2019 to focus on his research and teaching commitment.  As of July 1st, John Stobaugh assumed the role of interim director of HBC.  He is a professor of pharmaceutical chemistry and associate dean of research & graduate affairs in the School of Pharmacy.  He also serves as associate director of academic research at the HBC.

We would like to take this opportunity to thank Bill Picking for his service as director of the HBC for these past five years.

 

O’Leary Shared Service Center Satellite Office

This is a reminder that on July 17, 2019 the O’Leary Shared Service Center began to hold office hours in KU’s West District to facilitate in-person meetings for PI’s located in the district.  The satellite office is located in McCollum Laboratories, Room 129.  It is open the 1st and 3rd Wednesday of the month from 1 to 4 pm. 

 

Upcoming Fall Symposium

GRASP logoThe An HBC sponsored symposium is scheduled for this coming fall.   The 2019 Great Plains Regional Annual Symposium on Protein and Biomolecular NMR (GRASP NMR), a regional symposium on macromolecular NMR applications and techniques, will be held at the KU School of Pharmacy building on November 22 -23, 2019.  Registration is currently open and early-bird registration fees will be available until September 10, 2019.           

 

J.R. & Inez Jay Fund Research Awards   

Adam SmithMark Farrell

Two projects were selected this year to receive the 2019 J.R. and Inez Jay Fund research award at the University of Kansas. The first proposal selected, titled “Sugar coated vaccines for the treatment of opioid use disorder,” was submitted by Mark Farrell, assistant professor of medicinal chemistry, and Adam Smith, assistant professor of pharmacology and toxicology. The project will investigate a new approach to opioid conjugate vaccines.

Mark RichterThe second project selected was submitted by Mark Richter, professor of molecular biosciences.   The project, titled “Continuous monitoring of histamine in the brain,” will be conducted in collaboration with Candan Tamerler, professor of mechanical engineering, Paul Hanson, professor of chemistry, and George Wilson, distinguished professor emeritus of chemistry.   The proposal addresses the need for real-time continuous measurement of histamine levels in the brain and in other tissues as a biomarker and pre-indicator of multiple immunological, neurological, and cardiovascular disorders.

 

KU NIH Center of Biomedical Research Excellence (CoBRE) in Chemical Biology of Infectious Disease (CBID) Pilot Projects awards

The KU NIH CoBRE in Chemical Biology of Infectious Disease (CBID) received sixteen innovative and well qualified Pilot Project applications in February.  Out of the six selected proposals (four potential awards and two alternates) sent to NIH, four projects were approved.  They are:

  • Dr. Brian Ackley – University of Kansas, “On again, off again: Is pH a critical factor in pathogen killing?”
  • Dr. Josie Chandler – University of Kansas, “Chemical biology studies of malleilactone, a small-molecule toxin produced by Burkholderia pseudomallei”
  • Dr. Philip Hardwidge – Kansas State University, “Bacterial glycosyltransferase inhibitors as anti-virulence compounds”
  • Dr. Wolfram Zückert – University of Kansas Medical Center, “Small molecule inhibitors of bacterial surface lipoprotein secretion”

Congratulations to all.



HBC Events
Grant Submission Deadlines

September 18, 2019
AHA deadline for the Institutional Undergraduate Student Fellowship.

September 25, 2019
NIH Standard deadline for all Program Project Grants and Center Grants (P series) – new, renewals, resubmissions and revisions.

October 3, 2019
NIH deadline for the Maximizing Investigators' Research Award (R35) for Early Stage Investigators.

Recent Awards

Josephine Chandler, Assistant Professor, Department of Molecular Biosciences, was awarded $1,840,725 by the National Institutes of Health for her project entitled: “Quorum sensing evolution and function in mixed bacterial communities.”

Mark Farrell, Assistant Professor, Department of Medicinal Chemistry and Adam Smith, Assistant Professor of Pharmacology & Toxicology, were awarded $30,000 by the J.R. & Inez W. Jay Fund for their project entitled: “Sugar coated vaccines for the treatment of opioid use disorder.”

Audrey Lamb, Professor, Department of Molecular Biosciences, was awarded $400,000 by the National Science Foundation for her project entitled: “Collaborative Research: The Chemistry of Riboflavin Biosynthesis.”

Stuart Macdonald, Professor, Department of Molecular Biosciences, was awarded $122,836 by the National Institutes of Health as mentor to Elizabeth Everman for the project entitled: “Genetic dissection and characterization of variation in copper resistance in Drosophila melanogaster.”

Eli Michaelis, Research Professor, Higuchi Biosciences Center, was awarded $63,551 by KU Medical Center, for his project entitled: “KU ADC Mitochondrial Genomics and Metabolism Core Supplement.”

Mark Richter, Professor, Department of Molecular Biosciences, was awarded $30,000 by the J.R. & Inez W. Jay Fund for his project entitled: “Continuous monitoring of histamine in the brain.”

 

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