HBC January 2016 News Bulletin

Tuesday, January 19, 2016

Bill Picking

New Year’s Greetings from the Higuchi Biosciences Center

As we start a new year I would like to reflect a bit on the events of 2015.  My first full year at the helm of the HBC has been a tremendous learning experience, especially with university-wide reorganization of post-award services and the move of several of our staff members to the new Pharmacy & Biomedical Research Shared Service Center.  The PBR-SSC has now taken over many of the post-award activities that were previously handled by the HBC.  We continue with our quality service in proposal preparation and important activities that are part of the pre-award process.  Angela Loch and Jill McMillan were especially busy with budget preparation and proposal submissions in the area of biomedical research in 2015.  Extramural research funding opportunities continue to become increasingly challenging which has meant that new proposal submissions are on the rise.  Nevertheless, our investigators have been successful in keeping biomedical research strong on the KU Lawrence campus.  Awards to HBC investigators in 2015 have come from a variety of sources, including the PhRMA Foundation, the National Institutes of Health, the National Science Foundation, the American Chemical Society, Health Research Incorporated and industrial partners (http://hbc.ku.edu/list-recent-awards).  Our investigators have also taken advantage of partnerships with peer institutions and local funding sources such as the K-INBRE program to further the KU research mission.  To further enhance our investigators’ positioning for external funding, the HBC has continued to support early stage research via the J.R. and Inez Jay Fund and through contributions toward the purchase of small equipment.  The Jay Fund program was extremely competitive in 2015 and three awards were ultimately made to Laird Forrest (Pharmaceutical Chemistry), Mario Rivera (Chemistry) and Jeff Staudinger (Pharmacology and Toxicology).  The next Jay Fund competition will be announced soon.  Congratulations to these and all our outstanding researchers in their funding successes! 

The HBC has also been active in helping support seminars, symposia and meetings involving our investigators.  These have included our own Science Talks, the MIKI meeting for Medicinal Chemistry, the Great Plains Infectious Disease meeting, the Molecular Biosciences Graduate Student Symposium, the Great Plains Regional Annual Symposium on Protein and Biomolecular NMR, the NIGMS Annual Mentoring Workshop, the 2015 NIH Regional Seminar, and the Annual Carnival of Chemistry.  The HBC also partnered with Boehringer Ingelheim Vetmedica, Inc. and the Kansas Vaccine Institute to host the 2015 Community Practice Meeting in July.  We anticipate contributing further to hosting professional and outreach meetings in 2016 and are ready to consider other meeting ideas that our investigators might have.  The next Science Talks is scheduled for February 19 and will feature a blend of established and new investigators from the KU biomedical research community.  We look forward to seeing a good turnout from our HBC investigators and their research groups. 

As we look ahead, we plan to further enhance our services in proposal preparation, especially for our new investigators.  We have already made plans to participate in the preparation of future Center of Biomedical Excellence (CoBRE) proposals and are planning to host future short courses having biomedical research themes.  Some of the latter will be directed at enhancing the proposal writing skills of our new investigators.  Please look for announcements concerning these and other research promoting activities in the coming year.

So from our HBC staff, we wish you a productive 2016 and beyond,

 

William D. Picking, Director
Higuchi Biosciences Center

 

 

NIH Proposal Guidelines Changes effective January 2016

 This is a reminder that phase I of NIH’s modifications to proposal guidelines will be effective for all applications submitted on or after January 25, 2016.  The changes are as follow:

  • Enhancing Reproducibility through Rigor and Transparency
  • Decreasing of paperwork for the vertebrate animals section
  • Lowering of children age definition from 21 to 18 years old

For more detail, please visit the KU Office of research webpage.



Grant Submission Deadlines

March 5, 2021
NIH standard deadline for Research Grants and Cooperative Agreements (R01 and U01) – renewal, resubmission, revision.

March 11, 2021
DoD Breast Cancer Breakthrough Award Levels 1 & 2 & Era of Hope Scholar Award – Pre-application.

March 12, 2021
DoD Breast Cancer Breakthrough Award Levels 3 & 4  & Innovator Award – Pre-application.

March 16, 2021
NIH standard deadline for Other Research Grants and Cooperative Agreements (R03, R21, R33, R21/R33, R34, R36, UH2, UH3, UH2/UH3) – renewal, resubmission, revision.

Recent Awards

Yoshiaki Azuma, Professor, Department of Molecular Biosciences, was awarded $35,000 by the University of Kansas Medical Center Research Institute for his project entitled “Targeting mitotic function of the PICH (Polo-like kinase interacting checkpoint helicase) for novel therapeutics of TNBC.”

Heng Du, Associate Professor, Department of Pharmacology & Toxicology, transferred a grant from  the University of Dallas, Texas.  It is a BrightFocus Foundation project entitled “Synaptic mitochondrial calcium uniporter deregulation and synaptic injury in Alzheimer's disease.”

Teruna Siahaan, Aya and Takeru Higuchi Distinguished Professor and Associate Chair, Department of Pharmaceutical Chemistry, was awarded $25,000 by the PHRMA Foundation as mentor for Kelly Schwinghamer for the project entitled “Non-Invasive Brain Delivery Clearance  and Efficacy of Therapeutic Antibodies in Mice.”

Liang Xu, Professor, Department of Molecular Biosciences, was awarded $35,000 by the University of Kansas Medical Center Research Institute for his project entitled “Drug the Undruggable Musashi Oncoprotein by Fragment-based Drug Discovery.”

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