Of Note at Higuchi Biosciences Center - University of Kansas

Recent Publications

June 2009

- Lee J, Ham S, Im W.
Beta-hairpin restraint potentials for calculations of potentials of mean force as a function of beta-hairpin tilt, rotation, and distance.
J Comput Chem. 2009 Jun;30(8):1334-43. PMID: 19009593

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May 2009

- Oien DB, Canello T, Gabizon R, Gasset M, Lundquist BL, Burns JM, Moskovitz J.
Detection of oxidized methionine in selected proteins, cellular extracts and blood serums by novel anti-methionine sulfoxide antibodies.
Arch Biochem Biophys. 2009 May 1;485(1):35-40. PMID: 19388147

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April 2009

- Jiang X, Wang J, Luo T, Li Q.
Impaired hypothalamic-pituitary-adrenal axis and its feedback regulation in serotonin transporter knockout mice.
Psychoneuroendocrinology. 2009 Apr;34(3):317-31. Epub 2008 Nov 2. PMID: 18980809
- Xiong MP, Yáñez JA, Kwon GS, Davies NM, Forrest ML.
A cremophor-free formulation for tanespimycin (17-AAG) using PEO-b-PDLLA micelles: characterization and pharmacokinetics in rats.
J Pharm Sci. 2009 Apr;98(4):1577-86. PMID: 18752263

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March 2009

- Lichti-Kaiser K, Xu C, Staudinger JL.
Cyclic AMP-dependent protein kinase signaling modulates pregnane x receptor activity in a species-specific manner.
J Biol Chem. 2009 Mar 13;284(11):6639-49. Epub 2009 Jan 13. PMID: 19141612

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February 2009

- Liyanage MR, Zaidi A, Johnson CK.
Fluorescence polarization assay for calmodulin binding to plasma membrane Ca2+-ATPase: dependence on enzyme and Ca2+ concentrations.
Anal Biochem. 2009 Feb 1;385(1):1-6. Epub 2008 Nov 1. PMID: 19000896
- Lu Y, Ansar S, Michaelis ML, Blagg BS.
Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line.
Bioorg Med Chem. 2009 Feb 15;17(4):1709-15. Epub 2008 Dec 25. PMID: 19138859
- Luo BH, Karanicolas J, Harmacek LD, Baker D, Springer TA.
Rationally designed integrin beta3 mutants stabilized in the high affinity conformation.
J Biol Chem. 2009 Feb 6;284(6):3917-24. Epub 2008 Nov 19. PMID: 19019827
- Wang X, Zaidi A, Pal R, Garrett AS, Braceras R, Chen XW, Michaelis ML, Michaelis EK.
Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress.
BMC Neurosci. 2009 Feb 19;10:12. PMID: 19228403
- Zhou A, Rayabarapu D, Hanson PR.
"Click, click, cyclize": a DOS approach to sultams utilizing vinyl sulfonamide linchpins.
Org Lett. 2009 Feb 5;11(3):531-4. PMID: 19115841

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January 2009

- Hui D, Kumar KN, Mach JR, Srinivasan A, Pal R, Bao X, Agbas A, Höfner G, Wanner KT, Michaelis EK.
A rat brain bicistronic gene with an internal ribosome entry site codes for a phencyclidine-binding protein with cytotoxic activity.
J Biol Chem. 2009 Jan 23;284(4):2245-57. Epub 2008 Nov 21. PMID: 19028684.
- Simon JK, Wahid R, Maciel M Jr, Picking WL, Kotloff KL, Levine MM, Sztein MB.
Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidates.
Vaccine. 2009 Jan 22;27(4):565-72. Epub 2008 Nov 18. PMID: 19022324
- Zheng K, Middaugh CR, Siahaan TJ.
Evaluation of the physical stability of the EC5 domain of E-cadherin: effects of pH, temperature, ionic strength, and disulfide bonds.
J Pharm Sci. 2009 Jan;98(1):63-73. PMID: 18428798

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December 2008

- Chapman JO, Li H, Lundquist EA.
The MIG-15 NIK kinase acts cell-autonomously in neuroblast polarization and migration in C. elegans.
Dev Biol. 2008 Dec 15;324(2):245-57. Epub 2008 Sep 24. PMID: 18840424
- Ciaccio NA, Moreno ML, Bauer RL, Laurence JS.
High-yield expression in E. coli and refolding of the bZIP domain of activating transcription factor 5.
Protein Expr Purif. 2008 Dec;62(2):235-43. Epub 2008 Aug 3. PMID: 18718539
- Coltro WK, Lunte SM, Carrilho E.
Comparison of the analytical performance of electrophoresis microchannels fabricated in PDMS, glass, and polyester-toner.
Electrophoresis. 2008 Dec;29(24):4928-37. PMID: 19025869
- Bleiholder C, Osburn S, Williams TD, Suhai S, Van Stipdonk M, Harrison AG, Paizs B.
Sequence-scrambling fragmentation pathways of protonated peptides.
J Am Chem Soc. 2008 Dec 31;130(52):17774-89. PMID: 19055406
- DeVore NM, Smith BD, Urban MJ, Scott EE.
Key residues controlling phenacetin metabolism by human cytochrome P4502A enzymes.
Drug Metab Dispos. 2008 Dec;36(12):2582-90. Epub 2008 Sep 8. PMID: 18779312
- Sinha S, Li Y, Williams TD, Topp EM.
Protein conformation in amorphous solids by FTIR and by hydrogen/deuterium exchange with mass spectrometry.
Biophys J. 2008 Dec 15;95(12):5951-61. Epub 2008 Oct 3. PMID: 18835903
- Winefield RD, Entwistle RA, Foland TB, Lushington GH, Himes RH.
Differences in paclitaxel and docetaxel interactions with tubulin detected by mutagenesis of yeast tubulin.
ChemMedChem. 2008 Dec;3(12):1844-7. PMID: 18988212

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November 2008

- Barrett BS, Picking WL, Picking WD, Middaugh CR.
The response of type three secretion system needle proteins MxiHDelta5, BsaLDelta5, and PrgIDelta5 to temperature and pH.
Proteins. 2008 Nov 15;73(3):632-43. PMID: 18491382
- Boutell C, Everett R, Hilliard J, Schaffer P, Orr A, Davido D.
Herpes simplex virus type 1 ICP0 phosphorylation mutants impair the E3 ubiquitin ligase activity of ICP0 in a cell type-dependent manner.
J Virol. 2008 Nov;82(21):10647-56. Epub 2008 Aug 20. PMID: 18715910
- Fowler CJ, Haverlock TJ, Moyer BA, Shriver JA, Gross DE, Marquez M, Sessler JL, Hossain MA, Bowman-James K.
Enhanced anion exchange for selective sulfate extraction: overcoming the Hofmeister bias.
J Am Chem Soc. 2008 Nov 5;130(44):14386-7. Epub 2008 Oct 9. PMID: 18841965
- Hueston JL, Herren GP, Cueva JG, Buechner M, Lundquist EA, Goodman MB, Suprenant KA.
The C. elegans EMAP-like protein, ELP-1 is required for touch sensation and associates with microtubules and adhesion complexes.
BMC Dev Biol. 2008 Nov 17;8:110. PMID: 19014691
- Kim T, Lee J, Im W.
Molecular dynamics studies on structure and dynamics of phospholamban monomer and pentamer in membranes.
Proteins. 2008 Nov 6;76(1):86-98. [Epub ahead of print] PMID: 19089978
- Porubsky PR, Meneely KM, Scott EE.
Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates.
J Biol Chem. 2008 Nov 28;283(48):33698-707. Epub 2008 Sep 24. PMID: 18818195
- Rolfe A, Probst DA, Volp KA, Omar I, Flynn DL, Hanson PR.
High-load, oligomeric dichlorotriazine: a versatile ROMP-derived reagent and scavenger.
J Org Chem. 2008 Nov 21;73(22):8785-90. Epub 2008 Oct 21. PMID: 18937412
- Skinner AL, Laurence JS.
High-field solution NMR spectroscopy as a tool for assessing protein interactions with small molecule ligands.
J Pharm Sci. 2008 Nov;97(11):4670-95. PMID: 18351634

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October 2008

- Kobayashi N, Kiptoo P, Kobayashi H, Ridwan R, Brocke S, Siahaan TJ.
Prophylactic and therapeutic suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor.
Clin Immunol. 2008 Oct;129(1):69-79. Epub 2008 Aug 3. PMID: 18676182
- Seyb KI, Schuman ER, Ni J, Huang MM, Michaelis ML, Glicksman MA.
Identification of small molecule inhibitors of beta-amyloid cytotoxicity through a cell-based high-throughput screening platform.
J Biomol Screen. 2008 Oct;13(9):870-8. Epub 2008 Sep 23. PMID: 18812568
- Shi J, Landry M, Carrasco GA, Battaglia G, Muma NA.
Sustained treatment with a 5-HT(2A) receptor agonist causes functional desensitization and reductions in agonist-labeled 5-HT(2A) receptors despite increases in receptor protein levels in rats.
Neuropharmacology. 2008 Oct;55(5):687-92. Epub 2008 Jun 7. PMID: 18588902
- Terry CM, Picking WL, Birket SE, Flentie K, Hoffman BM, Barker JR, Picking WD.
The C-terminus of IpaC is required for effector activities related to Shigella invasion of host cells.
Microb Pathog. 2008 Oct;45(4):282-9. Epub 2008 Jul 4. PMID: 18656530
- Wang Y, Azuma Y, Moore D, Osheroff N, Neufeld KL.
Interaction between tumor suppressor adenomatous polyposis coli and topoisomerase IIalpha: implication for the G2/M transition.
Mol Biol Cell. 2008 Oct;19(10):4076-85. Epub 2008 Jul 16. PMID: 18632987

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September 2008

- Miller MA, Scott EE, Limburg J.
Expression, purification, crystallization and preliminary X-ray studies of a prolyl-4-hydroxylase protein from Bacillus anthracis.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Sep 1;64(Pt 9):788-91. Epub 2008 Aug 9. PMID: 18765905
- Rankin CA, Sun Q, Gamblin TC.
Pre-assembled tau filaments phosphorylated by GSK-3b form large tangle-like structures.
Neurobiol Dis. 2008 Sep;31(3):368-77. Epub 2008 Jul 16. PMID: 18588978
- Reed TM, Hirakawa H, Mure M, Scott EE, Limburg J.
Expression, purification, crystallization and preliminary X-ray studies of histamine dehydrogenase from Nocardioides simplex.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Sep 1;64(Pt 9):785-7. Epub 2008 Aug 9. PMID: 18765904
- Ying J, Sharov V, Xu S, Jiang B, Gerrity R, Schöneich C, Cohen RA.
Cysteine-674 oxidation and degradation of sarcoplasmic reticulum Ca(2+) ATPase in diabetic pig aorta.
Free Radic Biol Med. 2008 Sep 15;45(6):756-62. Epub 2008 Jun 13. PMID: 18590812

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August 2008

- Houndonougbo Y, Kuczera K, Jas GS.
Effects of CMAP and electrostatic cutoffs on the dynamics of an integral membrane protein: the phospholamban study.
J Biomol Struct Dyn. 2008 Aug;26(1):17-34. PMID: 18533723
- Jo S, Kim T, Iyer VG, Im W.
CHARMM-GUI: a web-based graphical user interface for CHARMM.
J Comput Chem. 2008 Aug;29(11):1859-65. PMID: 18351591
- Khalaf JK, VanderVelde DG, Datta A.
Synthetic studies on ezomycins: stereoselective route to a thymine octosyl nucleoside derivative.
J Org Chem. 2008 Aug 1;73(15):5977-84. Epub 2008 Jul 4. PMID: 18598087
- Lichti-Kaiser K, Staudinger JL.
The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes.
Drug Metab Dispos. 2008 Aug;36(8):1538-45. Epub 2008 May 12. PMID: 18474680
- Poon KW, Datta A.
A rapid synthetic route to conformationally restricted [5,5]-bicyclic nucleoside-amino acid conjugates.
Nucleosides Nucleotides Nucleic Acids. 2008 Aug;27(8):914-30. PMID: 18696362
- Rankin CA, Gamblin TC.
Assessing the toxicity of tau aggregation.
J Alzheimers Dis. 2008 Aug;14(4):411-6.PMID: 18688091
- Shakir MA, Jiang K, Struckhoff EC, Demarco RS, Patel FB, Soto MC, Lundquist EA.
The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance.
Genetics. 2008 Aug;179(4):1957-71. Epub 2008 Aug 9. PMID: 18689885
- Sun Q, Cai S, Peterson BR.
Selective disruption of early/recycling endosomes: release of disulfide-linked cargo mediated by a N-alkyl-3beta-cholesterylamine-capped peptide.
J Am Chem Soc. 2008 Aug 6;130(31):10064-5. Epub 2008 Jul 10. PMID: 18613675

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July 2008

- Dai Y, Dudek NL, Patel TB, Muma NA.
Transglutaminase-catalyzed transamidation: a novel mechanism for Rac1 activation by 5-hydroxytryptamine2A receptor stimulation.
J Pharmacol Exp Ther. 2008 Jul;326(1):153-62. Epub 2008 Apr 9. PMID: 18400843
- Entwistle RA, Winefield RD, Foland TB, Lushington GH, Himes RH.
The paclitaxel site in tubulin probed by site-directed mutagenesis of Saccharomyces cerevisiae beta-tubulin.
FEBS Lett. 2008 Jul 9;582(16):2467-70. Epub 2008 Jun 18. PMID: 18570892
- Ikehata K, Duzhak TG, Galeva NA, Ji T, Koen YM, Hanzlik RP.
Protein targets of reactive metabolites of thiobenzamide in rat liver in vivo.
Chem Res Toxicol. 2008 Jul;21(7):1432-42. Epub 2008 Jun 12. PMID: 18547066
- Iskandarsyah, Tejo BA, Tambunan US, Verkhivker G, Siahaan TJ.
Structural modifications of ICAM-1 cyclic peptides to improve the activity to inhibit heterotypic adhesion of T cells.
Chem Biol Drug Des. 2008 Jul;72(1):27-33. Epub 2008 Jun 11. PMID: 18554252
- Jo S, Vargyas M, Vasko-Szedlar J, Roux B, Im W.
PBEQ-Solver for online visualization of electrostatic potential of biomolecules.
Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W270-5. Epub 2008 May 28. PMID: 18508808.
- Kang SO, Day VW, Bowman-James K.
Cyclophane capsule motifs with side pockets.
Org Lett. 2008 Jul 3;10(13):2677-80. Epub 2008 Jun 6. PMID: 18533666
- Lee J, Chen J, Brooks CL 3rd, Im W.
Application of solid-state NMR restraint potentials in membrane protein modeling.
J Magn Reson. 2008 Jul;193(1):68-76. Epub 2008 Apr 18. PMID: 18462966
- Mozziconacci O, Sharov V, Williams TD, Kerwin BA, Schöneich C.
Peptide cysteine thiyl radicals abstract hydrogen atoms from surrounding amino acids: the photolysis of a cystine containing model peptide.
J Phys Chem B. 2008 Jul 31;112(30):9250-7. Epub 2008 Jul 9. PMID: 18611046
- Oien DB, Osterhaus GL, Latif SA, Pinkston JW, Fulks J, Johnson M, Fowler SC, Moskovitz J.
MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels.
Free Radic Biol Med. 2008 Jul 15;45(2):193-200. Epub 2008 Apr 15. PMID: 18466776
- Porubsky PR, Scott EE, Williams TD.
p-dimethylaminocinnamaldehyde derivatization for colorimetric detection and HPLC-UV/vis-MS/MS identification of indoles.
Arch Biochem Biophys. 2008 Jul 1;475(1):14-7. Epub 2008 Apr 7. PMID: 18423367
- Rathinavelan T, Im W.
A novel strategy to determine protein structures using exclusively residual dipolar coupling.
J Comput Chem. 2008 Jul 30;29(10):1640-9. PMID: 18293296
- Stensrud KF, Adam PR, La Mar CD, Olive AJ, Lushington GH, Sudharsan R, Shelton NL, Givens RS, Picking WL, Picking WD.
Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip.
J Biol Chem. 2008 Jul 4;283(27):18646-54. Epub 2008 May 1. PMID: 18450744
- Stoianova DS, Yao L, Rolfe A, Samarakoon T, Hanson PR.
High-load, oligomeric monoamine hydrochloride: Facile generation via ROM polymerization and application as an electrophile scavenger.
Tetrahedron Lett. 2008;49(29-30):4553-4555. PMID: 19319202
- Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB.
Genes contributing to prion pathogenesis.
J Gen Virol. 2008 Jul;89(Pt 7):1777-88. PMID: 18559949
- Verkhivker G, Tiana G, Camilloni C, Provasi D, Broglia RA.
Atomistic simulations of the HIV-1 protease folding inhibition.
Biophys J. 2008 Jul;95(2):550-62. Epub 2008 Mar 28. PMID: 18375506
- Wilson GS, Johnson MA.
In-vivo electrochemistry: what can we learn about living systems?
Chem Rev. 2008 Jul;108(7):2462-81. Epub 2008 Jun 18. PMID: 18558752
- Xiong MP, Yáñez JA, Remsberg CM, Ohgami Y, Kwon GS, Davies NM, Forrest ML.
Formulation of a geldanamycin prodrug in mPEG-b-PCL micelles greatly enhances tolerability and pharmacokinetics in rats.
J Control Release. 2008 Jul 2;129(1):33-40. Epub 2008 Mar 25. PMID: 18456363
- Yang Q, Li Y, Dou D, Gan X, Mohan S, Groutas CS, Stevenson LE, Lai Z, Alliston KR, Zhong J, Williams TD, Groutas WC.
Inhibition of serine proteases by a new class of cyclosulfamide-based carbamylating agents.
Arch Biochem Biophys. 2008 Jul 15;475(2):115-20. Epub 2008 Apr 22. PMID: 18457652
- Zhou A, Hanson PR.
Synthesis of sultam scaffolds via intramolecular oxa-Michael and diastereoselective Baylis-Hillman reactions.
Org Lett. 2008 Jul 17;10(14):2951-4. Epub 2008 Jun 14. PMID: 18553974

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June 2008

- Cai S, Xie Y, Bagby TR, Cohen MS, Forrest ML.
Intralymphatic chemotherapy using a hyaluronan-cisplatin conjugate.
J Surg Res. 2008 Jun 15;147(2):247-52. Epub 2008 Mar 26. PMID: 18498877
-Colombo G, Morra G, Meli M, Verkhivker G.
Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution.
Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):7976-81. Epub 2008 May 29. PMID: 18511558
- Jiménez-Hopkins M, Hanson PR.
An RCM strategy to stereodiverse delta-sultam scaffolds.
Org Lett. 2008 Jun 5;10(11):2223-6. Epub 2008 May 1. PMID: 18447383
- Kimbrell MR, Warshakoon H, Cromer JR, Malladi S, Hood JD, Balakrishna R, Scholdberg TA, David SA.
Comparison of the immunostimulatory and proinflammatory activities of candidate Gram-positive endotoxins, lipoteichoic acid, peptidoglycan, and lipopeptides, in murine and human cells.
Immunol Lett. 2008 Jun 30;118(2):132-41. Epub 2008 Apr 18. PMID: 18468694. PMCID: PMC2491907
- Markham AP, Birket SE, Picking WD, Picking WL, Middaugh CR.
pH sensitivity of type III secretion system tip proteins.
Proteins. 2008 Jun;71(4):1830-42. PMID: 18175320
- Schöneich C.
Mechanisms of protein damage induced by cysteine thiyl radical formation.
Chem Res Toxicol. 2008 Jun;21(6):1175-9. Epub 2008 Mar 25. PMID: 18361510
- Stauffer CS, Datta A.
Synthetic studies on amipurimycin: total synthesis of a thymine nucleoside analogue.
J Org Chem. 2008 Jun 6;73(11):4166-74. Epub 2008 May 9. PMID: 18465899
- Yu C, Rouen S, Dobrowsky RT.
Hyperglycemia and downregulation of caveolin-1 enhance neuregulin-induced demyelination.
Glia. 2008 Jun;56(8):877-87. PMID: 18338795

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May 2008

- Bhunia A, Chua GL, Domadia PN, Warshakoon H, Cromer JR, David SA, Bhattacharjya S.
Interactions of a designed peptide with lipopolysaccharide: Bound conformation and anti-endotoxic activity.
Biochem Biophys Res Commun. 2008 May 9;369(3):853-7. Epub 2008 Mar 5. PMID: 18328260
- Forrest ML, Kwon GS.
Clinical developments in drug delivery nanotechnology.
Adv Drug Deliv Rev. 2008 May 22;60(8):861-2. Epub 2008 Mar 5. PMID: 18358557
- Lee J, Im W.
Role of hydrogen bonding and helix-lipid interactions in transmembrane helix association.
J Am Chem Soc. 2008 May 21;130(20):6456-62. Epub 2008 Apr 19. PMID: 18422318
- Lu J, Dentler WL, Lundquist EA.
FLI-1 Flightless-1 and LET-60 Ras control germ line morphogenesis in C. elegans.
BMC Dev Biol. 2008 May 16;8:54. PMID: 18485202
- Stensrud KF, Heger D, Sebej P, Wirz J, Givens RS.
Fluorinated photoremovable protecting groups: the influence of fluoro substituents on the photo-Favorskii rearrangement.
Photochem Photobiol Sci. 2008 May;7(5):614-24. Epub 2008 Apr 3. PMID: 18465018
- Vega-Villa KR, Takemoto JK, Yáñez JA, Remsberg CM, Forrest ML, Davies NM.
Clinical toxicities of nanocarrier systems.
Adv Drug Deliv Rev. 2008 May 22;60(8):929-38. Epub 2008 Feb 7. PMID: 18313790

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April 2008

- Dudek NL, Dai Y, Muma NA.
Protective effects of interrupting the binding of calmodulin to mutant huntingtin.
J Neuropathol Exp Neurol. 2008 Apr;67(4):355-65. PMID: 18379433
- Hu C, Fang J, Borchardt RT, Schowen RL, Kuczera K.
Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution.
Proteins. 2008 Apr;71(1):131-43. PMID: 17932938
- Huang W, Yamamoto Y, Li Y, Dou D, Alliston KR, Hanzlik RP, Williams TD, Groutas WC.
X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives.
J Med Chem. 2008 Apr 10;51(7):2003-8. Epub 2008 Mar 5. PMID: 18318470
- Jain HD, Zhang C, Zhou S, Zhou H, Ma J, Liu X, Liao X, Deveau AM, Dieckhaus CM, Johnson MA, Smith KS, Macdonald TL, Kakeya H, Osada H, Cook JM.
Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein.
Bioorg Med Chem. 2008 Apr 15;16(8):4626-51. Epub 2008 Feb 20. PMID: 18321710
- Li QS, Cai S, Fang J, Borchardt RT, Kuczera K, Middaugh CR, Schowen RL.
Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 2. The role of helix 18 stability.
Biochemistry. 2008 Apr 29;47(17):4983-91. Epub 2008 Apr 8. PMID: 18393535
- Martin A, David V, Laurence JS, Schwarz PM, Lafer EM, Hedge AM, Rowe PS.
Degradation of MEPE, DMP1, and Release of SIBLING ASARM-Peptides (Minhibins): ASARM-Peptide(s) Are Directly Responsible for Defective Mineralization in HYP.
Endocrinology. 2008 Apr;149(4):1757-72. Epub 2007 Dec 27. PMID: 18162525
- Pinto C, Papa D, Hübner M, Mou TC, Lushington GH, Seifert R.
Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs.
J Pharmacol Exp Ther. 2008 Apr;325(1):27-36. Epub 2008 Jan 9. PMID: 18184830
- Poon KW, Liang N, Datta A.
De novo synthetic route to a combinatorial library of peptidyl nucleosides.
Nucleosides Nucleotides Nucleic Acids. 2008 Apr;27(4):389-407. PMID: 18404573
- Whitehead A, Waetzig JD, Thomas CD, Hanson PR.
A multifaceted phosphate tether: application to the C15-C30 subunit of dolabelides A-D.
Org Lett. 2008 Apr 3;10(7):1421-4. Epub 2008 Mar 7. PMID: 18324822

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March 2008

- Burlison JA, Avila C, Vielhauer G, Lubbers DJ, Holzbeierlein J, Blagg BS.
Development of novobiocin analogues that manifest anti-proliferative activity against several cancer cell lines.
J Org Chem. 2008 Mar 21;73(6):2130-7. Epub 2008 Feb 23. PMID: 18293999
- Fenster E, Rayabarapu DK, Zhang M, Mukherjee S, Hill D, Neuenswander B, Schoenen F, Hanson PR, Aubé J.
Three-component synthesis of 1,4-diazepin-5-ones and the construction of gamma-turn-like peptidomimetic libraries.
J Comb Chem. 2008 Mar-Apr;10(2):230-4. Epub 2008 Feb 7. PMID: 18254600
- Givens RS, Heger D, Hellrung B, Kamdzhilov Y, Mac M, Conrad PG 2nd, Cope E, Lee JI, Mata-Segreda JF, Schowen RL, Wirz J.
The photo-Favorskii reaction of p-hydroxyphenacyl compounds is initiated by water-assisted, adiabatic extrusion of a triplet biradical.
J Am Chem Soc. 2008 Mar 19;130(11):3307-9. Epub 2008 Feb 22. PMID: 18290649.
- Li K, Tunge JA.
Chemical libraries via sequential C-H functionalization of phenols.
J Comb Chem. 2008 Mar-Apr;10(2):170-4. Epub 2008 Jan 31. PMID: 18237144
- Mandal A, Liyanage MR, Zaidi A, Johnson CK.
Interchange of autoinhibitory domain conformations in plasma-membrane Ca2+-ATPase-calmodulin complexes.
Protein Sci. 2008 Mar;17(3):555-62. Epub 2008 Jan 24. PMID: 18218717
- Shrestha A, Li R, Sil D, Pardeshi NN, Schwarting N, Schorno KS, Rajewski RA, Datta A, David SA.
Pharmacokinetics of DS-96, an alkylpolyamine lipopolysaccharide sequestrant, in rodents.
J Pharm Sci. 2008 Mar 27. [Epub ahead of print]. PMID: 18383338
- Tian J, Stella VJ.
Degradation of paclitaxel and related compounds in aqueous solutions I: Epimerization.
J Pharm Sci. 2008 Mar;97(3):1224-35. PMID: 17680660
- Vedantham P, Guerra JM, Schoenen F, Huang M, Gor PJ, Georg GI, Wang JL, Neuenswander B, Lushington GH, Mitscher LA, Ye QZ, Hanson PR.
Ionic immobilization, diversification, and release: application to the generation of a library of methionine aminopeptidase inhibitors.
J Comb Chem. 2008 Mar-Apr;10(2):185-94. Epub 2007 Dec 29. PMID: 18163595
- Vedantham P, Zhang M, Gor PJ, Huang M, Georg GI, Lushington GH, Mitscher LA, Ye QZ, Hanson PR.
Studies towards the synthesis of methionine aminopeptidase inhibitors: diversification utilizing a ROMP-derived coupling reagent.
J Comb Chem. 2008 Mar-Apr;10(2):195-203. Epub 2007 Dec 29. PMID: 18163595
- Zhang L, Lushington GH, Neuenswander B, Hershberger JC, Malinakova HC.
Solution-phase parallel synthesis of hexahydro-1H-isoindolone libraries via tactical combination of Cu-catalyzed three-component coupling and Diels-Alder reactions.
J Comb Chem. 2008 Mar-Apr;10(2):285-302. Epub 2008 Feb 1. PMID: 18237142

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February 2008

- Cohen MS, Cai S, Xie Y, Forrest ML.
Nanocarrier-conjugated intralymphatic chemotherapy: a novel approach to breast cancer treatment.
J. Surg. Res. 2008 Feb;144(2):439.
- Fang J, Dong Y, Williams TD, Lushington GH.
Feature selection in validating mass spectrometry database search results.
J Bioinform Comput Biol. 2008 Feb;6(1):223-40. PMID: 18324754
- Harraz MM, Marden JJ, Zhou W, Zhang Y, Williams A, Sharov VS, Nelson K, Luo M, Paulson H, Schöneich C, Engelhardt JF.
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model.
J Clin Invest. 2008 Feb;118(2):659-70. PMID: 18219391
- Li Y, Williams TD, Topp EM.
Effects of excipients on protein conformation in lyophilized solids by hydrogen/deuterium exchange mass spectrometry.
Pharm Res. 2008 Feb;25(2):259-67. Epub 2007 Jun 28. PMID: 17597380
- Oien DB, Moskovitz J.
Substrates of the methionine sulfoxide reductase system and their physiological relevance.
Curr Top Dev Biol. 2008;80:93-133. Review. PMID: 17950373
- Otrubova K, Lushington G, Vander Velde D, McGuire KL, McAlpine SR.
Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines.
J Med Chem. 2008 Feb 14;51(3):530-44. Epub 2008 Jan 11. PMID: 18186604
- Park SH, Cheong C, Idoyaga J, Kim JY, Choi JH, Do Y, Lee H, Jo JH, Oh YS, Im W, Steinman RM, Park CG.
Generation and application of new rat monoclonal antibodies against synthetic FLAG and OLLAS tags for improved immunodetection.
J Immunol Methods. 2008 Feb 29;331(1-2):27-38. Epub 2007 Nov 26. PMID: 18054954

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January 2008

- Bassan M, Liu H, Madsen KL, Armsen W, Zhou J, Desilva T, Chen W, Paradise A, Brasch MA, Staudinger J, Gether U, Irwin N, Rosenberg PA.
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1.
Eur J Neurosci. 2008 Jan;27(1):66-82. PMID: 18184314
- Druar C, Yu F, Barnes JL, Okinaka RT, Chantratita N, Beg S, Stratilo CW, Olive AJ, Soltes G, Russell ML, Limmathurotsakul D, Norton RE, Ni SX, Picking WD, Jackson PJ, Stewart DI, Tsvetnitsky V, Picking WL, Cherwonogrodzky JW, Ketheesan N, Peacock SJ, Wiersma EJ.
Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents.
FEMS Immunol Med Microbiol. 2008 Jan;52(1):78-87. Epub 2007 Nov 11. PMID: 17995960
- Forrest ML, Yáñez JA, Remsberg CM, Ohgami Y, Kwon GS, Davies NM.
Paclitaxel prodrugs with sustained release and high solubility in poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelle nanocarriers: pharmacokinetic disposition, tolerability, and cytotoxicity.
Pharm Res. 2008 Jan;25(1):194-206. Epub 2007 Oct 3. PMID: 17912488
- Givens RS, Yousef AL, Yang S, Timberlake GT.
Collagen cross linking agents: design and development of a multifunctional cross linker.
Photochem Photobiol. 2008 Jan-Feb;84(1):185-92. PMID: 18173719
- Hastings JM, Hadden MK, Blagg BS.
Synthesis and evaluation of derrubone and select analogues.
J Org Chem. 2008 Jan 18;73(2):369-73. Epub 2007 Dec 22. PMID: 18154304
- He F, Samra HS, Johnson EA, Degner NR, McCarty RE, Richter ML.
C-Terminal mutations in the chloroplast ATP synthase gamma subunit impair ATP synthesis and stimulate ATP hydrolysis.
Biochemistry. 2008 Jan 15;47(2):836-44. Epub 2007 Dec 20. PMID: 18092810
- Lee J, Im W.
Transmembrane helix tilting: insights from calculating the potential of mean force.
Phys Rev Lett. 2008 Jan 11;100(1):018103. Epub 2008 Jan 8. PMID: 18232823
- Poon KW, Lovell KM, Dresner KN, Datta A.
Trimethylsilyl trifluoromethanesulfonate (TMSOTf) assisted facile deprotection of N,O-acetonides.
J Org Chem. 2008 Jan 18;73(2):752-5. Epub 2007 Dec 13. PMID: 18076188
- Staudinger JL.
Liver-enriched nuclear receptors: therapeutic opportunities.
Mol Pharm. 2008 Jan-Feb;5(1):1-2. PMID: 18247475
- Staudinger JL, Lichti K.
Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.
Mol Pharm. 2008 Jan-Feb;5(1):17-34. Epub 2007 Dec 27. PMID: 18159925
- Waetzig JD, Hanson PR.
A multifaceted phosphate tether: application to the C1-C14 subunit of dolabelides A-D.
Org Lett. 2008 Jan 3;10(1):109-12. Epub 2007 Dec 7. PMID: 18062695
- Yáñez JA, Forrest ML, Ohgami Y, Kwon GS, Davies NM.
Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin.
Cancer Chemother Pharmacol. 2008 Jan;61(1):133-44. Epub 2007 Mar 29. PMID: 17393166
- Zhang N, Chittasupho C, Duangrat C, Siahaan TJ, Berkland C.
PLGA nanoparticle--peptide conjugate effectively targets intercellular cell-adhesion molecule-1.
Bioconjug Chem. 2008 Jan;19(1):145-52. Epub 2007 Nov 13. PMID: 17997512

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December 2007

- Cai S, Li QS, Borchardt RT, Kuczera K, Schowen RL.
The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi.
Bioorg Med Chem. 2007 Dec 1;15(23):7281-7. Epub 2007 Aug 24. PMID: 17845853
- Hadden MK, Galam L, Gestwicki JE, Matts RL, Blagg BS.
Derrubone, an inhibitor of the Hsp90 protein folding machinery.
J Nat Prod. 2007 Dec;70(12):2014-8. Epub 2007 Nov 17. PMID: 18020309
- Johnson MA, Villanueva M, Haynes CL, Seipel AT, Buhler LA, Wightman RM.
Catecholamine exocytosis is diminished in R6/2 Huntington's disease model mice.
J Neurochem. 2007 Dec;103(5):2102-10. Epub 2007 Sep 14. PMID: 17868298
- Stauffer CS, Bhaket P, Fothergill AW, Rinaldi MG, Datta A.
Total synthesis and antifungal activity of a carbohydrate ring-expanded pyranosyl nucleoside analogue of nikkomycin B.
J Org Chem. 2007 Dec 21;72(26):9991-7. Epub 2007 Nov 15. PMID: 18001102
- Waetzig SR, Tunge JA.
Palladium-catalyzed decarboxylative sp3-sp3 coupling of nitrobenzene acetic esters.
J Am Chem Soc. 2007 Dec 5;129(48):14860-1. Epub 2007 Nov 8. PMID: 17988134

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November 2007

- Hopkins CD, Malinakova HC.
Synthesis of Unnatural a-Amino Acid Derivatives via a Three-Component Coupling Method Utilizing an Allylpalladium Umpolung.
Synthesis. 2007, Nov;22:3558-3566.
- Kotloff KL, Simon JK, Pasetti MF, Sztein MB, Wooden SL, Livio S, Nataro JP, Blackwelder WC, Barry EM, Picking W, Levine MM.
Safety and immunogenicity of CVD 1208S, a live, oral DeltaguaBA Deltasen Deltaset Shigella flexneri 2a vaccine grown on animal-free media.
Hum Vaccin. 2007 Nov-Dec;3(6):268-75. Epub 2007 Jul 15. PMID: 17938573
- Xiong, M.P., M.L. Forrest, G. Ton, A. Zhao, N.M. Davies, G.S. Kwon.
Poly(aspartate-g-PEI800), a polyethylenimine analogue of low toxicity and high transfection efficiency for gene delivery.
Biomaterials. 2007 Nov;28(32):4889-4900.
- Zhang L, Wang Y, Olive AJ, Smith ND, Picking WD, De Guzman RN, Picking WL.
Identification of the MxiH needle protein residues responsible for anchoring invasion plasmid antigen D to the type III secretion needle tip.
J Biol Chem. 2007 Nov 2;282(44):32144-51. Epub 2007 Sep 7. PMID: 17827155
- Williams RB, Gutekunst WR, Joyner PM, Duan W, Li Q, Ross CA, Williams TD, Cichewicz RH.
Bioactivity profiling with parallel mass spectrometry reveals an assemblage of green tea metabolites affording protection against human huntingtin and alpha-synuclein toxicity.
J Agric Food Chem. 2007 Nov 14;55(23):9450-6. Epub 2007 Oct 19. PMID: 17944533

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October 2007

- Bogard N, Lan L, Xu J, Cohen RS.
Rab11 maintains connections between germline stem cells and niche cells in the Drosophila ovary.
Development. 2007 Oct;134(19):3413-8. Epub 2007 Aug 22. PMID: 17715175
- Buszek KR, Luo D, Kondrashov M, Brown N, VanderVelde D.
Indole-derived arynes and their Diels-Alder reactivity with furans.
Org Lett. 2007 Oct 11;9(21):4135-7. Epub 2007 Sep 19. PMID: 17880092
- Dremina ES, Sharov VS, Davies MJ, Schöneich C.
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides.
Chem Res Toxicol. 2007 Oct;20(10):1462-9. Epub 2007 Sep 25. PMID: 17892267
- Fischer CJ, Saha A, Cairns BR.
Kinetic model for the ATP-dependent translocation of Saccharomyces cerevisiae RSC along double-stranded DNA.
Biochemistry. 2007 Oct 30;46(43):12416-26. Epub 2007 Oct 5. PMID: 17918861
- Huang R, Lu Z, Dai H, Velde DV, Prakash O, Jiang H.
The solution structure of clip domains from Manduca sexta prophenoloxidase activating proteinase-2.
Biochemistry. 2007 Oct 16;46(41):11431-9. Epub 2007 Sep 19. PMID: 17880110
- Meneely KM, Lamb AL.
Biochemical characterization of a flavin adenine dinucleotide-dependent monooxygenase, ornithine hydroxylase from Pseudomonas aeruginosa, suggests a novel reaction mechanism.
Biochemistry. 2007 Oct 23;46(42):11930-7. Epub 2007 Sep 28. PMID: 17900176
- Shi J, Damjanoska KJ, Singh RK, Carrasco GA, Garcia F, Grippo AJ, Landry M, Sullivan NR, Battaglia G, Muma NA.
Agonist induced-phosphorylation of Galpha11 protein reduces coupling to 5-HT2A receptors.
J Pharmacol Exp Ther. 2007 Oct;323(1):248-56. Epub 2007 Jul 23. PMID: 17646429
- Xiong H, Zhang Y, Chen XW.
Data-dependent kernel machines for microarray data classification.
IEEE/ACM Trans Comput Biol Bioinform. 2007 Oct-Dec;4(4):583-95. PMID: 17975270

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September 2007

- Hadden MK, Blagg BS.
Cytotoxic small molecule dimers and their inhibitory activity against human breast cancer cells.
Bioorg Med Chem Lett. 2007 Sep 15;17(18):5063-7. Epub 2007 Jul 13. PMID: 17656092
- Jo S, Kim T, Im W.
Automated builder and database of protein/membrane complexes for molecular dynamics simulations.
PLoS ONE. 2007 Sep 12;2(9):e880. PMID: 17849009
- Moore RH, Spies MA, Culpepper MB, Murakawa T, Hirota S, Okajima T, Tanizawa K, Mure M.
Trapping of a dopaquinone intermediate in the TPQ cofactor biogenesis in a copper-containing amine oxidase from Arthrobacter globiformis.
J Am Chem Soc. 2007 Sep 19;129(37):11524-34. Epub 2007 Aug 23. PMID: 17715921
- Muma NA, Singh RK, Vercillo MS, D'Souza DN, Zemaitaitis B, Garcia F, Damjanoska KJ, Zhang Y, Battaglia G, Van de Kar LD.
Chronic olanzapine activates the Stat3 signal transduction pathway and alters expression of components of the 5-HT2A receptor signaling system in rat frontal cortex.
Neuropharmacology. 2007 Sep;53(4):552-62. Epub 2007 Jul 1. PMID: 17675105
- Nguyen TB, Adisechan AK, Suresh Kumar EV, Balakrishna R, Kimbrell MR, Miller KA, Datta A, David SA.
Protection from endotoxic shock by EVK-203, a novel alkylpolyamine sequestrant of lipopolysaccharide.
Bioorg Med Chem. 2007 Sep 1;15(17):5694-709. Epub 2007 Jun 10. PMID: 17583517
- Sotthivirat S, Haslam JL, Stella VJ.
Controlled porosity-osmotic pump pellets of a poorly water-soluble drug using sulfobutylether-beta-cyclodextrin, (SBE) 7M-beta-CD, as a solubilizing and osmotic agent.
J Pharm Sci. 2007 Sep;96(9):2364-74. PMID: 17497739
- Wang JL, Datta A, Lushington GH.
Structure-Based Quantitative Structure Activity Relationship Analysis of Omuralide Analogs in the 20S Proteasome: A Covalent Inhibitor COMBINE Study.
Lett. Drug Design. 2007 Sep;4(6):417-21.
- Xiong MP, Bae Y, Fukushima S, Forrest ML, Nishiyama N, Kataoka K, Kwon GS.
pH-Responsive Multi-PEGylated Dual Cationic Nanoparticles Enable Charge Modulations for Safe Gene Delivery.
ChemMedChem. 2007 Sep;2(9):1321-7. PMID: 17579918
- Yusuf-Makagiansar H, Yakovleva TV, Tejo BA, Jones K, Hu Y, Verkhivker GM, Audus KL, Siahaan TJ.
Sequence recognition of alpha-LFA-1-derived peptides by ICAM-1 cell receptors: inhibitors of T-cell adhesion.
Chem Biol Drug Des. 2007 Sep;70(3):237-46. PMID: 17718718.

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August 2007

- Arnold MM, Gorman EM, Schieber LJ, Munson EJ, Berkland C.
NanoCipro encapsulation in monodisperse large porous PLGA microparticles.
J Control Release. 2007 Aug 16;121(1-2):100-9. Epub 2007 Jun 13. PMID: 17604870
- Bobrowski K, Hug GL, Pogocki D, Marciniak B, Schöneich C.
Stabilization of sulfide radical cations through complexation with the peptide bond: mechanisms relevant to oxidation of proteins containing multiple methionine residues.
J Phys Chem B. 2007 Aug 16;111(32):9608-20. Epub 2007 Jul 21. PMID: 17658786
- Carey AN, Borozny K, Aldrich JV, McLaughlin JP.
Reinstatement of cocaine place-conditioning prevented by the peptide kappa-opioid receptor antagonist arodyn.
Eur J Pharmacol. 2007 Aug 13;569(1-2):84-9. Epub 2007 May 13. PMID: 17568579
- Denora N, Potts BC, Stella VJ.
A mechanistic and kinetic study of the beta-lactone hydrolysis of Salinosporamide A (NPI-0052), a novel proteasome inhibitor.
J Pharm Sci. 2007 Aug;96(8):2037-47. PMID: 17554770
- Kobayashi N, Kobayashi H, Gu L, Malefyt T, Siahaan TJ.
Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor.
J Pharmacol Exp Ther. 2007 Aug;322(2):879-86. Epub 2007 May 23. PMID: 17522343
Li Q, Deng X, Singh P.
Significant increase in the aggressive behavior of transgenic mice overexpressing peripheral progastrin peptides: associated changes in CCK2 and serotonin receptors in the CNS.
Neuropsychopharmacology. 2007 Aug;32(8):1813-21. Epub 2007 Jan 17. PMID: 17228339
- Rathinavelan T, Im W.
Explicit treatment of force contribution from alignment tensor using overdetermined linear equations and its application in NMR structure determination.
J Comput Chem. 2007 Aug;28(11):1858-64. PMID: 17405113
- Rytting E, Audus KL.
Effects of low oxygen levels on the expression and function of transporter OCTN2 in BeWo cells.
J Pharm Pharmacol. 2007 Aug;59(8):1095-102. PMID: 17725851
- Sil D, Shrestha A, Kimbrell MR, Nguyen TB, Adisechan AK, Balakrishna R, Abbo BG, Malladi S, Miller KA, Short S, Cromer JR, Arora S, Datta A, David SA.
Bound to shock: protection from lethal endotoxemic shock by a novel, nontoxic, alkylpolyamine lipopolysaccharide sequestrant.
Antimicrob Agents Chemother. 2007 Aug;51(8):2811-9. Epub 2007 Jun 4. PMID: 17548488
- Verkhivker GM.
Exploring sequence-structure relationships in the tyrosine kinome space: functional classification of the binding specificity mechanisms for cancer therapeutics.
Bioinformatics. 2007 Aug 1;23(15):1919-26. Epub 2007 May 30. PMID: 17537753
- Wang Y, Ouellette AN, Egan CW, Rathinavelan T, Im W, De Guzman RN.
Differences in the electrostatic surfaces of the type III secretion needle proteins PrgI, BsaL, and MxiH.
J Mol Biol. 2007 Aug 31;371(5):1304-14. Epub 2007 Jun 15. PMID: 17617421
- Wang X, Pal R, Chen XW, Kumar KN, Kim OJ, Michaelis EK.
Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampus.
Genomics. 2007 Aug;90(2):201-12. Epub 2007 Jun 5. PMID: 17553663
- Wang Y, Ouellette AN, Egan CW, Rathinavelan T, Im W, De Guzman RN.
Differences in the electrostatic surfaces of the type III secretion needle proteins PrgI, BsaL, and MxiH.
J Mol Biol. 2007 Aug 31;371(5):1304-14. Epub 2007 Jun 15. PMID: 17617421

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July 2007

- Agbas A, Hui D, Wang X, Tek V, Zaidi A, Michaelis EK.
Activation of brain calcineurin (Cn) by Cu-Zn superoxide dismutase (SOD1) depends on direct SOD1-Cn protein interactions occurring in vitro and in vivo.
Biochem J. 2007 Jul 1;405(1):51-9. PMID: 17324120
- Birket SE, Harrington AT, Espina M, Smith ND, Terry CM, Darboe N, Markham AP, Middaugh CR, Picking WL, Picking WD.
Preparation and characterization of translocator/chaperone complexes and their component proteins from Shigella flexneri.
Biochemistry. 2007 Jul 10;46(27):8128-37. Epub 2007 Jun 16. PMID: 17571858
- Bobrowski K, Hug GL, Pogocki D, Marciniak B, Schöneich C.
Sulfur radical cation-peptide bond complex in the one-electron oxidation of S-methylglutathione.
J Am Chem Soc. 2007 Jul 25;129(29):9236-45. Epub 2007 Jun 29. PMID: 17602483
- Carlson SW, Branden M, Voss K, Sun Q, Rankin CA, Gamblin TC.
A complex mechanism for inducer mediated tau polymerization.
Biochemistry. 2007 Jul 31;46(30):8838-49. Epub 2007 Jul 4. PMID: 17608454
- Fernandes D, Zaidi A, Bean J, Hui D, Michaelis ML.
RNA--induced silencing of the plasma membrane Ca2+-ATPase 2 in neuronal cells: effects on Ca2+ homeostasis and cell viability.
J Neurochem. 2007 Jul;102(2):454-65. Epub 2007 May 4. PMID: 17488275
- Guo R, Portscheller JL, Day VW, Malinakova HC.
An Allylpalladium(IV) Intermediate in the Synthesis of Highly Substituted Benzoxepines and Benzopyrans via Reactions of Stable Pallada(II)cycles with Allyl Bromides.
Organometallics. 2007 Jul 16;26:3874-83.
- Jiang L, Fernandes D, Mehta N, Bean JL, Michaelis ML, Zaidi A.
Partitioning of the plasma membrane Ca2+-ATPase into lipid rafts in primary neurons: effects of cholesterol depletion.
J Neurochem. 2007 Jul;102(2):378-88. PMID: 17596212
- Lushington GH, Guo JX, Wang JL.
Whither combine? New opportunities for receptor-based QSAR.
Curr Med Chem. 2007;14(17):1863-77. Review. PMID: 17627522
- Wakankar AA, Liu J, Vandervelde D, Wang YJ, Shire SJ, Borchardt RT.
The effect of cosolutes on the isomerization of aspartic acid residues and conformational stability in a monoclonal antibody.
J Pharm Sci. 2007 Jul;96(7):1708-18. PMID: 17238195

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June 2007

- Bishop SC, Burlison JA, Blagg BS.
Hsp90: a novel target for the disruption of multiple signaling cascades.
Curr Cancer Drug Targets. 2007 Jun;7(4):369-88. Review. PMID: 17979631
- Fried KW, Schneider CM, Schramm KW, Datta A, Chahbane N, Corsten C, Powell DR, Lenoir D, Kettrup A, Terranova P, Georg GI, Rozman KK.
From Dioxin to Drug Lead-The Development of 2,3,7,8-Tetrachlorophenothiazine.
ChemMedChem. 2007 Jun 11;2(6):890-897. PMID: 17394264
- Lee J. and Im W.
Restrain Potential and Free Energy Decomposition for Helical Tilting.
Chem. Phys. Lett. 2007 Jun 13;441:132-35.
- McIntosh MP, Carlson BJ, Schorno KS, Rajewski RA.
Single quadrupole mass spectrometry for pre-clinical pharmacokinetic analysis: quantitation of carvedilol in dog plasma.
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 1;852(1-2):665-8. Epub 2007 Feb 20. PMID: 17468057
- Pal R, Oien DB, Ersen FY, Moskovitz J.
Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase A knockout mouse.
Exp Brain Res. 2007 Jul;180(4):765-74. Epub 2007 Feb 28. PMID: 17333008
- Prudic KL, Khera S, Sólyom A, Timmermann BN.
Isolation, identification, and quantification of potential defensive compounds in the viceroy butterfly and its larval host-plant, Carolina willow.
J Chem Ecol. 2007 Jun;33(6):1149-59. Epub 2007 Apr 13. PMID: 17431749
- Rankin CA, Sun Q, Gamblin TC.
Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology.
Mol Neurodegener. 2007 Jun 28;2:12. PMID: 17598919
- Smith BD, Sanders JL, Porubsky PR, Lushington GH, Stout CD, Scott EE.
Structure of the human lung cytochrome P450 2A13.
J Biol Chem. 2007 Jun 8;282(23):17306-13. Epub 2007 Apr 11. PMID: 17428784
- Tarca AL, Carey VJ, Chen XW, Romero R, Drăghici S.
Machine learning and its applications to biology.
PLoS Comput Biol. 2007 Jun;3(6):e116. Review. PMID: 17604446

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May 2007

- Butler D, Bendiske J, Michaelis ML, Karanian DA, Bahr BA.
Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers.
Eur J Pharmacol. 2007 May 7;562(1-2):20-7. Epub 2007 Feb 8. PMID: 17336290
- Chaudhry P, Schoenen F, Neuenswander B, Lushington GH, Aubé J.
One-step synthesis of oxazoline and dihydrooxazine libraries.
J Comb Chem. 2007 May-Jun;9(3):473-6. Epub 2007 Mar. PMID: 17391008
- Dickenson NE, Moore D, Suprenant KA, Dunn RC.
Vault ribonucleoprotein particles and the central mass of the nuclear pore complex.
Photochem Photobiol. 2007 May-Jun;83(3):686-91. PMID: 17576379
- Huang YT, Blagg BS.
A library of noviosylated coumarin analogues.
J Org Chem. 2007 May 11;72(10):3609-13. Epub 2007 Mar 1. PMID: 17328573
- Lee YJ, Miyake S, Wakita H, McMullen DC, Azuma Y, Auh S, Hallenbeck JM.
Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells.
J Cereb Blood Flow Metab. 2007 May;27(5):950-62. Epub 2006 Sep 6. PMID: 16955077
- Li QS, Cai S, Borchardt RT, Fang J, Kuczera K, Middaugh CR, Schowen RL.
Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 1. Basic features of the association and dissociation processes.
Biochemistry. 2007 May 15;46(19):5798-809. Epub 2007 Apr 21. PMID: 17447732
- McIntosh MP, Narita H, Kameyama Y, Rajewski RA, Goto H.
Evaluation of mean arterial blood pressure, heart rate, and sympathetic nerve activity in rabbits after administration of two formulations of etomidate.
Vet Anaesth Analg. 2007 May;34(3):149-56. PMID: 17444927
- Oien D, Moskovitz J.
Protein-carbonyl accumulation in the non-replicative senescence of the methionine sulfoxide reductase A (msrA) knockout yeast strain.
Amino Acids. 2007;32(4):603-6. Epub 2006 Nov 3. PMID: 17077964
- Olive AJ, Kenjale R, Espina M, Moore DS, Picking WL, Picking WD.
Bile salts stimulate recruitment of IpaB to the Shigella flexneri surface, where it colocalizes with IpaD at the tip of the type III secretion needle.
Infect Immun. 2007 May;75(5):2626-9. Epub 2007 Feb 12. PMID: 17296762
- Sotthivirat S, Lubach JW, Haslam JL, Munson EJ, Stella VJ.
Characterization of prednisolone in controlled porosity osmotic pump pellets using solid-state NMR spectroscopy.
J Pharm Sci. 2007 May;96(5):1008-17. PMID: 17455361
- Tomko EJ, Fischer CJ, Niedziela-Majka A, Lohman TM.
A nonuniform stepping mechanism for E. coli UvrD monomer translocation along single-stranded DNA.
Mol Cell. 2007 May 11;26(3):335-47. PMID: 17499041
- Xiong MP, Forrest ML, Karls AL, Kwon GS.
Biotin-triggered release of poly(ethylene glycol)-avidin from biotinylated polyethylenimine enhances in vitro gene expression.
Bioconjug Chem. 2007 May-Jun;18(3):746-53. Epub 2007 Mar 22. PMID: 17375897

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April 2007

- Ansar S, Burlison JA, Hadden MK, Yu XM, Desino KE, Bean J, Neckers L, Audus KL, Michaelis ML, Blagg BS.
A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity.
Bioorg Med Chem Lett. 2007 Apr 1;17(7):1984-90. Epub 2007 Jan 17. PMID: 17276679.
- Dutta D, Datta A, Vander Velde DG, Georg GI.
Oxidation of baccatin III at C14: A facile rearrangement of the baccatin III core.
Lett. Org. Chem. 2007 Apr;4(3):151-54.
- Espina M, Ausar SF, Middaugh CR, Baxter MA, Picking WD, Picking WL.
Conformational stability and differential structural analysis of LcrV, PcrV, BipD, and SipD from type III secretion systems.
Protein Sci. 2007 Apr;16(4):704-14. Epub 2007 Feb 27. PMID: 17327391
- Harsay E, Schekman R.
Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway.
Mol Biol Cell. 2007 Apr;18(4):1203-19. Epub 2007 Jan 17. PMID: 17229886
- Hsu FF, Turk J, Williams TD, Welti R.
Electrospray ionization multiple stage quadrupole ion-trap and tandem quadrupole mass spectrometric studies on phosphatidylglycerol from Arabidopsis leaves.
J Am Soc Mass Spectrom. 2007 Apr;18(4):783-90. Epub 2007 Feb 14. PMID: 17303435
- Ji T, Ikehata K, Koen YM, Esch SW, Williams TD, Hanzlik RP.
Covalent modification of microsomal lipids by thiobenzamide metabolites in vivo.
Chem Res Toxicol. 2007 Apr;20(4):701-8. Epub 2007 Mar 24. PMID: 17381136
- Lubach JW, Xu D, Segmuller BE, Munson EJ.
Investigation of the effects of pharmaceutical processing upon solid-state NMR relaxation times and implications to solid-state formulation stability.
J Pharm Sci. 2007 Apr;96(4):777-87. PMID: 17238201
- Sharov VS, Schöneich C.
Proteomic approach to aging research.
Expert Rev Proteomics. 2007 Apr;4(2):309-21. Review. PMID: 17425465
- Tian F, Middaugh CR, Offerdahl T, Munson E, Sane S, Rytting JH.
Spectroscopic evaluation of the stabilization of humanized monoclonal antibodies in amino acid formulations.
Int J Pharm. 2007 Apr 20;335(1-2):20-31. Epub 2006 Oct 29. PMID: 17141436
- Wang H, Huang H, Li H, Teotico DG, Sinz M, Baker SD, Staudinger J, Kalpana G, Redinbo MR, Mani S.
Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.
Clin Cancer Res. 2007 Apr 15;13(8):2488-95. PMID: 17438109
- Wang JL, Guo JX, Zhang QY, Wu JJ, Seifert R, Lushington GH.
A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified and unmodified nucleotide inhibitors.
Bioorg Med Chem. 2007 Apr 15;15(8):2993-3002. Epub 2007 Feb 11. PMID: 17329110
- Zhang M, Flynn DL, Hanson PR.
Oligomeric benzylsulfonium salts: facile benzylation via high-load ROMP reagents.
J Org Chem. 2007 Apr 27;72(9):3194-8. Epub 2007 Apr 4. PMID: 17407352
- Zhang Y, Illarionov B, Bacher A, Fischer M, Georg GI, Ye QZ, Vander Velde D, Fanwick PE, Song Y, Cushman M.
A novel lumazine synthase inhibitor derived from oxidation of 1,3,6,8-tetrahydroxy-2,7-naphthyridine to a tetraazaperylenehexaone derivative.
J Org Chem. 2007 Apr 13;72(8):2769-76. Epub 2007 Mar 10. PMID: 17348709

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March 2007

- Chappa AK, Cooper JD, Audus KL, Lunte SM.
Investigation of the metabolism of substance P at the blood-brain barrier using LC-MS/MS.
J Pharm Biomed Anal. 2007 Mar 12;43(4):1409-15. Epub 2006 Nov 21. PMID: 17118606.
- Chen XW, Gerlach B, Chen D, Liu Z.
Structural Risk Minimisation based gene expression profiling analysis.
Int J Bioinform Res Appl. 2007;3(2):153-69. PMID: 18048186
- Christianson JA, Ryals JM, Johnson MS, Dobrowsky RT, Wright DE.
Neurotrophic modulation of myelinated cutaneous innervation and mechanical sensory loss in diabetic mice.
Neuroscience. 2007 Mar 2;145(1):303-13. Epub 2006 Dec 16. PMID: 17223273
- Cooper JD, Heppert KE, Davies MI, Lunte SM.
Evaluation of an osmotic pump for microdialysis sampling in an awake and untethered rat.
J Neurosci Methods. 2007 Mar 15;160(2):269-75. Epub 2006 Oct 31. PMID: 17079021, PMCID: PMC1945051
- Galam L, Hadden MK, Ma Z, Ye QZ, Yun BG, Blagg BS, Matts RL.
High-throughput assay for the identification of Hsp90 inhibitors based on Hsp90-dependent refolding of firefly luciferase.
Bioorg Med Chem. 2007 Mar 1;15(5):1939-46. Epub 2007 Jan 4. PMID: 17223347
- Gokulrangan G, Zaidi A, Michaelis ML, Schöneich C.
Proteomic analysis of protein nitration in rat cerebellum: effect of biological aging.
J Neurochem. 2007 Mar;100(6):1494-504. Epub 2007 Jan 24. PMID: 17254026
- Hanzlik RP, Koen YM, Theertham B, Dong Y, Fang J.
The reactive metabolite target protein database (TPDB)--a web-accessible resource.
BMC Bioinformatics. 2007 Mar 16;8:95. PMID: 17367530
- He F, Samra HS, Tucker WC, Mayans DR, Hoang E, Gromet-Elhanan Z, Berrie CL, Richter ML.
Mutations within the C-terminus of the gamma subunit of the photosynthetic F1-ATPase activate MgATP hydrolysis and attenuate the stimulatory oxyanion effect.
Biochemistry. 2007 Mar 6;46(9):2411-8. Epub 2007 Feb 9. PMID: 17288458
- Koen YM, Gogichaeva NV, Alterman MA, Hanzlik RP.
A proteomic analysis of bromobenzene reactive metabolite targets in rat liver cytosol in vivo.
Chem Res Toxicol. 2007 Mar;20(3):511-9. Epub 2007 Feb 17. PMID: 17305373
- Rytting E, Bryan J, Southard M, Audus KL.
Low-affinity uptake of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (4-Di-1-ASP) in BeWo cells.
Biochem Pharmacol. 2007 Mar 15;73(6):891-900. Epub 2006 Dec 1. PMID: 17174940.
- Suprenant KA, Bloom N, Fang J, Lushington G.
The major vault protein is related to the toxic anion resistance protein (TelA) family.
J Exp Biol. 2007 Mar;210(Pt 6):946-55. PMID: 17337707
- Uthus EO, Moskovitz J.
Specific activity of methionine sulfoxide reductase in CD-1 mice is significantly affected by dietary selenium but not zinc.
Biol Trace Elem Res. 2007 Mar;115(3):265-76. PMID: 17625247
- Yao L, Aubé J.
Cation-pi control of regiochemistry of intramolecular schmidt reactions en route to bridged bicyclic lactams.
J Am Chem Soc. 2007 Mar 14;129(10):2766-7. Epub 2007 Feb 16. PMID: 17302421

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February 2007

- Bu L, Im W, Brooks CL 3rd.
Membrane assembly of simple helix homo-oligomers studied via molecular dynamics simulations.
Biophys J. 2007 Feb 1;92(3):854-63. Epub 2006 Nov 3. PMID: 17085501
- Burns MR, Jenkins SA, Kimbrell MR, Balakrishna R, Nguyen TB, Abbo BG, David SA.
Polycationic sulfonamides for the sequestration of endotoxin.
J Med Chem. 2007 Feb 22;50(4):877-88. Epub 2007 Jan 26. PMID: 17256835
- Johnson S, Roversi P, Espina M, Olive A, Deane JE, Birket S, Field T, Picking WD, Blocker AJ, Galyov EE, Picking WL, Lea SM.
Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.
J Biol Chem. 2007 Feb 9;282(6):4035-44. Epub 2006 Oct 31. PMID: 17077085
- Lee J, Im W.
Implementation and application of helix-helix distance and crossing angle restraint potentials.
J Comput Chem. 2007 Feb;28(3):669-80. PMID: 17195157
- Moskovitz J.
Prolonged selenium-deficient diet in MsrA knockout mice causes enhanced oxidative modification to proteins and affects the levels of antioxidant enzymes in a tissue-specific manner.
Free Radic Res. 2007 Feb;41(2):162-71. PMID: 17364942
- Sotthivirat S, Haslam JL, Stella VJ.
Evaluation of various properties of alternative salt forms of sulfobutylether-beta-cyclodextrin, (SBE)7M-beta-CD.
Int J Pharm. 2007 Feb 7;330(1-2):73-81. Epub 2006 Sep 16. PMID: 17045435
- Wakankar AA, Borchardt RT, Eigenbrot C, Shia S, Wang YJ, Shire SJ, Liu JL.
Aspartate isomerization in the complementarity-determining regions of two closely related monoclonal antibodies.
Biochemistry. 2007 Feb 13;46(6):1534-44. Epub 2007 Jan 17. PMID: 17279618
- Zhang L, Malinakova HC.
Copper-catalyzed multicomponent cascade process for the synthesis of hexahydro-1H-isoindolones.
J Org Chem. 2007 Feb 16;72(4):1484-7. Epub 2007 Jan 23. PMID: 17243720

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January 2007

- Ahn YM, Vogeti L, Liu CJ, Santhapuram HK, White JM, Vasandani V, Mitscher LA, Lushington GH, Hanson PR, Powell DR, Himes RH, Roby KF, Ye Q, Georg GI.
Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues.
Bioorg Med Chem. 2007 Jan 15;15(2):702-13. Epub 2006 Nov 1. PMID: 17123821
- Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW.
Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
Drug Metab Dispos. 2007 Jan;35(1):36-42. Epub 2006 Oct 4. PMID: 17020958
- Esch SW, Tamura P, Sparks AA, Roth MR, Devaiah SP, Heinz E, Wang X, Williams TD, Welti R.
Rapid characterization of the fatty acyl composition of complex lipids by collision-induced dissociation time-of-flight mass spectrometry.
J Lipid Res. 2007 Jan;48(1):235-41. Epub 2006 Oct 19. PMID: 17053274
- Huang H, Wang H, Sinz M, Zoeckler M, Staudinger J, Redinbo MR, Teotico DG, Locker J, Kalpana GV, Mani S.
Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole.
Oncogene. 2007 Jan 11;26(2):258-68. Epub 2006 Jul 3. PMID: 16819505
- Manyem S, Sibi MP, Lushington GH, Neuenswander B, Schoenen F, Aubé J.
Solution-phase parallel synthesis of a library of delta(2)-pyrazolines.
J Comb Chem. 2007 Jan-Feb;9(1):20-8. PMID: 17206829
- Oien DB, Moskovitz J.
Ablation of the mammalian methionine sulfoxide reductase A affects the expression level of cysteine deoxygenase.
Biochem Biophys Res Commun. 2007 Jan 12;352(2):556-9. Epub 2006 Nov 20. PMID: 17126812
- Seyb KI, Ansar S, Li G, Bean J, Michaelis ML, Dobrowsky RT.
p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide.
J Mol Neurosci. 2007;31(1):23-36. PMID: 17416967

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December 2006

- Burlison JA, Neckers L, Smith AB, Maxwell A, Blagg BS.
Novobiocin: redesigning a DNA gyrase inhibitor for selective inhibition of hsp90.
J Am Chem Soc. 2006 Dec 6;128(48):15529-36. PMID: 17132020
- Burns MR, Jenkins SA, Vermeulen NM, Balakrishna R, Nguyen TB, Kimbrell MR, David SA.
Structural correlation between lipophilicity and lipopolysaccharide-sequestering activity in spermine-sulfonamide analogs.
Bioorg Med Chem Lett. 2006 Dec 15;16(24):6209-12. Epub 2006 Sep 28. PMID: 17010608
- Chaudhury S, Welch TR, Blagg BS.
Hsp90 as a target for drug development.
ChemMedChem. 2006 Dec;1(12):1331-40. Review. PMID: 17066389
- Díaz-Martínez LA, Giménez-Abián JF, Azuma Y, Guacci V, Giménez-Martín G, Lanier LM, Clarke DJ.
PIASgamma is required for faithful chromosome segregation in human cells.
PLoS ONE. 2006 Dec 20;1:e53. PMID: 17183683
- Hopkins CD, Malinakova HC.
Allylpalladium umpolung in the three-component coupling synthesis of homoallylic amines.
Org Lett. 2006 Dec 21;8(26):5971-4. PMID: 17165907
- Johnson CK.
Calmodulin, conformational states, and calcium signaling. A single-molecule perspective.
Biochemistry. 2006 Dec 5;45(48):14233-46. PMID: 17128963
- Kamerzell TJ, Unruh JR, Johnson CK, Middaugh CR.
Conformational flexibility, hydration and state parameter fluctuations of fibroblast growth factor-10: effects of ligand binding.
Biochemistry. 2006 Dec 26;45(51):15288-300. PMID: 17176051
- Sieck S, McReynolds MD, Schroeder CE, Hanson PR.
Metathesis Studies to Cyclic Enol Phosphonamidates.
J. Organomet. Chem.2006 Dec 1;691(24-25):5307-5311.
- Staudinger JL, Ding X, Lichti K.
Pregnane X receptor and natural products: beyond drug-drug interactions.
Expert Opin Drug Metab Toxicol. 2006 Dec;2(6):847-57. Review. PMID: 17125405
- Xiong Y, Chen B, Smallwood HS, Urbauer RJ, Markille LM, Galeva N, Williams TD, Squier TC.
High-affinity and cooperative binding of oxidized calmodulin by methionine sulfoxide reductase.
Biochemistry. 2006 Dec 12;45(49):14642-54. PMID: 17144657
- Yang Y, Lu J, Rovnak J, Quackenbush SL, Lundquist EA.
SWAN-1, a Caenorhabditis elegans WD repeat protein of the AN11 family, is a negative regulator of Rac GTPase function.
Genetics. 2006 Dec;174(4):1917-32. Epub 2006 Sep 15. PMID: 16980389

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November 2006

- Huynh BH, Fogarty BA, Nandi P, Lunte SM.
A microchip electrophoresis device with on-line microdialysis sampling and on-chip sample derivatization by naphthalene 2,3-dicarboxaldehyde/2-mercaptoethanol for amino acid and peptide analysis.
J Pharm Biomed Anal. 2006 Nov 16;42(5):529-34. Epub 2006 Jul 10. PMID: 16829012
- Koen YM, Yue W, Galeva NA, Williams TD, Hanzlik RP.
Site-specific arylation of rat glutathione s-transferase A1 and A2 by bromobenzene metabolites in vivo.
Chem Res Toxicol. 2006 Nov;19(11):1426-34. PMID: 17112229
- Laursen JB, Nielsen J, Haack T, Pusuluri S, David S, Balakrishna R, Zeng Y, Ma Z, Doyle TB, Mitscher LA.
Further exploration of antimicrobial ketodihydronicotinic acid derivatives by multiple parallel syntheses.
Comb Chem High Throughput Screen. 2006 Nov;9(9):663-81. PMID: 17100572
- Lucas AN, Tanol M, McIntosh MP, Rajewski RA.
Preparation and purification of desethylamiodarone hydrochloride.
Synthetic Communications. 2006 Nov 1;36(22):3371-76.
- Schöneich C, Sharov VS.
Mass spectrometry of protein modifications by reactive oxygen and nitrogen species.
Free Radic Biol Med. 2006 Nov 15;41(10):1507-20. Epub 2006 Aug 16. Review. PMID: 17045919
- Unruh JR, Price ES, Molla RG, Hui R, Johnson CK.
Evaluation of a femtosecond fiber laser for two-photon fluorescence correlation spectroscopy.
Microsc Res Tech. 2006 Nov;69(11):891-3. PMID: 16886226
- Wakankar AA, Borchardt RT.
Formulation considerations for proteins susceptible to asparagine deamidation and aspartate isomerization.
J Pharm Sci. 2006 Nov;95(11):2321-36. Review. PMID: 16960822
- Zaitseva J, Lu J, Olechoski KL, Lamb AL.
Two crystal structures of the isochorismate pyruvate lyase from Pseudomonas aeruginosa.
J Biol Chem. 2006 Nov 3;281(44):33441-9. Epub 2006 Aug 16. PMID: 16914555

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October 2006

- Barich DH, Gorman EM, Zell MT, Munson EJ.
3-Methylglutaric acid as a 13C solid-state NMR standard.
Solid State Nucl Magn Reson. 2006 Oct;30(3-4):125-9. Epub 2006 Jun 15. PMID: 16887343
- Burger EC, Barron BR, Tunge JA.
Catalytic Asymmetric Synthesis of Cyclic a-Allylated a-Fluoroketones.
Synlett 2006 Oct;17:2824-26.
- Burlison JA, Blagg BS.
Synthesis and evaluation of coumermycin A1 analogues that inhibit the Hsp90 protein folding machinery.
Org Lett. 2006 Oct 12;8(21):4855-8. PMID: 17020320
- Cheng Q, Benson DR, Rivera M, Kuczera K.
Influence of point mutations on the flexibility of cytochrome b5: molecular dynamics simulations of holoproteins.
Biopolymers. 2006 Oct 15;83(3):297-312. PMID: 16807901
- Judd WR, Ban S, Aubé J.
Remote control of diastereoselectivity in intramolecular reactions of chiral allylsilanes.
J Am Chem Soc. 2006 Oct 25;128(42):13736-41. PMID: 17044701
- He HT, Gürsoy RN, Kupczyk-Subotkowska L, Tian J, Williams T, Siahaan TJ.
Synthesis and chemical stability of a disulfide bond in a model cyclic pentapeptide: cyclo(1,4)-Cys-Gly-Phe-Cys-Gly-OH.
J Pharm Sci. 2006 Oct;95(10):2222-34. PMID: 16883561
- Li K, Vanka K, Thompson WH, Tunge JA.
Stereochemical control in the reduction of 2-chromanols.
Org Lett. 2006 Oct 12;8(21):4711-4. PMID: 17020284
- Samra HS, Gao F, He F, Hoang E, Chen Z, Gegenheimer PA, Berrie CL, Richter ML.
Structural analysis of the regulatory dithiol-containing domain of the chloroplast ATP synthase gamma subunit.
J Biol Chem. 2006 Oct 13;281(41):31041-9. Epub 2006 Aug 8. PMID: 16895914
- Unruh JR, Price ES, Molla RG, Stehno-Bittel L, Johnson CK, Hui R.
Two-Photon Microscopy with Wavelength Switchable Fiber Laser Excitation.
Optics Express 2006 Oct 16;14(21):9825-31.
- von Montfort C, Sharov VS, Metzger S, Schöneich C, Sies H, Klotz LO.
Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine.
Biol Chem. 2006 Oct-Nov;387(10-11):1399-404. PMID: 17081112
- Whitehead A, McParland JP, Hanson PR.
Divalent activation in temporary phosphate tethers: highly selective cuprate displacement reactions.
Org Lett. 2006 Oct 26;8(22):5025-8. PMID: 17048834

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September 2006

- Buseman CM, Tamura P, Sparks AA, Baughman EJ, Maatta S, Zhao J, Roth MR, Esch SW, Shah J, Williams TD, Welti R.
Wounding stimulates the accumulation of glycerolipids containing oxophytodienoic acid and dinor-oxophytodienoic acid in Arabidopsis leaves.
Plant Physiol. 2006 Sep;142(1):28-39. Epub 2006 Jul 14. PMID: 16844834
- Ding X, Lichti K, Kim I, Gonzalez FJ, Staudinger JL.
Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha.
J Biol Chem. 2006 Sep 8;281(36):26540-51. Epub 2006 Jul 5. PMID: 16825189
- Dunehoo AL, Anderson M, Majumdar S, Kobayashi N, Berkland C, Siahaan TJ.
Cell adhesion molecules for targeted drug delivery.
J Pharm Sci. 2006 Sep;95(9):1856-72. Review. Erratum in: J Pharm Sci. 2007 Jan;96(1):234. PMID: 16850395
- Herpel RH, Vedantham P, Flynn DL, Hanson PR.
High-Load, Oligomeric Phosphonyl Dichloride: Facile Generation via ROM Polymerization and Application to Scavenging Amines.
Tetrahedron Lett. 2006 Sep 4;47(36):6429-6432.
- Johnson S, Roversi P, Espina M, Deane JE, Birket S, Picking WD, Blocker A, Picking WL, Lea SM.
Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt 9):865-8. Epub 2006 Aug 11. PMID: 16946465
- Mou TC, Gille A, Suryanarayana S, Richter M, Seifert R, Sprang SR.
Broad specificity of mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors.
Mol Pharmacol. 2006 Sep;70(3):878-86. Epub 2006 Jun 9. PMID: 16766715
- Mukhopadhyay D, Ayaydin F, Kolli N, Tan SH, Anan T, Kametaka A, Azuma Y, Wilkinson KD, Dasso M.
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species.
J Cell Biol. 2006 Sep 25;174(7):939-49. PMID: 17000875
- Shen G, Wang M, Welch TR, Blagg BS.
Design, synthesis, and structure – activity relationships for chimeric inhibitors of Hsp90.
J Org Chem. 2006 Sep 29;71(20):7618-31. PMID: 16995666

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August 2006

- Burger EC, Tunge JA.
Synthesis of homoallylic amines via the palladium-catalyzed decarboxylative coupling of amino acid derivatives.
J Am Chem Soc. 2006 Aug 9;128(31):10002-3. PMID: 16881615
- Deane JE, Roversi P, Cordes FS, Johnson S, Kenjale R, Daniell S, Booy F, Picking WD, Picking WL, Blocker AJ, Lea SM.
Molecular model of a type III secretion system needle: Implications for host-cell sensing.
Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12529-33. Epub 2006 Aug 3. PMID: 16888041
- Espina M, Ausar SF, Middaugh CR, Picking WD, Picking WL.
Spectroscopic and calorimetric analyses of invasion plasmid antigen D (IpaD) from Shigella flexneri reveal the presence of two structural domains.
Biochemistry. 2006 Aug 1;45(30):9219-27. PMID: 16866368
- Espina M, Olive AJ, Kenjale R, Moore DS, Ausar SF, Kaminski RW, Oaks EV, Middaugh CR, Picking WD, Picking WL.
IpaD localizes to the tip of the type III secretion system needle of Shigella flexneri.
Infect Immun. 2006 Aug;74(8):4391-400. PMID: 16861624
- Sacksteder CA, Whittier JE, Xiong Y, Li J, Galeva NA, Jacoby ME, Purvine SO, Williams TD, Rechsteiner MC, Bigelow DJ, Squier TC.
Tertiary structural rearrangements upon oxidation of Methionine145 in calmodulin promotes targeted proteasomal degradation.
Biophys J. 2006 Aug 15;91(4):1480-93. Epub 2006 Jun 2. PMID: 16751245
- Yu M, Malinakova HC, Stagliano KW.
A new method for the synthesis of 2-hydroxy-3-nitro-1,4-naphthoquinones: application to regiospecific preparation of unsymmetrical nitrobiquinones.
J Org Chem. 2006 Aug 18;71(17):6648-51. PMID: 16901163

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July 2006

- Anderson ME, Tejo BA, Yakovleva T, Siahaan TJ.
Characterization of binding properties of ICAM-1 peptides to LFA-1: inhibitors of T-cell adhesion.
Chem Biol Drug Des. 2006 Jul;68(1):20-8. PMID: 16923022
- Barich DH, Davis JM, Schieber LJ, Zell MT, Munson EJ.
Investigation of solid-state NMR line widths of ibuprofen in drug formulations.
J Pharm Sci. 2006 Jul;95(7):1586-94. PMID: 16732561
- Houndonougbo Y, Jiu H, Rajagopalan B, Wong K, Kuczera K, Subramaniam B, Laird B.
Phase equilibria in carbon-dioxide expanded solvents: Experiments and molecular simulations.
J. Phys. Chem. B. 2006 Jul 6;110(26):13195-202.
- Liu Y, Scolari M, Im W, Woo HJ.
Protein-protein interactions in actin-myosin binding and structural effects of R405Q mutation: a molecular dynamics study.
Proteins. 2006 Jul 1;64(1):156-66. PMID: 16645962
- Quillen EE, Haslam GC, Samra HS, Amani-Taleshi D, Knight JA, Wyatt DE, Bishop SC, Colvert KK, Richter ML, Kitos PA.
Ectoadenylate kinase and plasma membrane ATP synthase activities of human vascular endothelial cells.
J Biol Chem. 2006 Jul 28;281(30):20728-37. Epub 2006 May 19. PMID: 16714292
- Waetzig SR, Rayabarapu DK, Weaver JD, Tunge JA.
A versatile hexadiene synthesis by decarboxylative sp(3)-sp(3) coupling/cope rearrangement.
Angew Chem Int Ed Engl. 2006 Jul 24;45(30):4977-80. PMID: 16819739
- Wang C, Tunge JA.
Decarboxylative ring contractions and olefin insertions of vinyl oxazinanones.
Org Lett. 2006 Jul 20;8(15):3211-4. PMID: 16836368

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June 2006

- Avila C, Hadden MK, Ma Z, Kornilayev BA, Ye QZ, Blagg BS.
High-throughput screening for Hsp90 ATPase inhibitors.
Bioorg Med Chem Lett. 2006 Jun 1;16(11):3005-8. Epub 2006 Mar 10. PMID: 16530412
- Chappa AK, Audus KL, Lunte SM.
Characteristics of substance P transport across the blood-brain barrier.
Pharm Res. 2006 Jun;23(6):1201-8. Epub 2006 Jun 1. PMID: 16729222.
- Chen XW, Anantha G, Wang X.
An effective structure learning method for constructing gene networks.
Bioinformatics. 2006 Jun 1;22(11):1367-74. Epub 2006 Mar 16. PMID: 16543279
- Ding X, Lichti K, Staudinger JL.
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
Toxicol Sci. 2006 Jun;91(2):448-55. Epub 2006 Mar 17. PMID: 16547076
- Duvvuri M, Konkar S, Hong KH, Blagg BS, Krise JP.
A new approach for enhancing differential selectivity of drugs to cancer cells.
ACS Chem Biol. 2006 Jun 20;1(5):309-15. PMID: 17163760
- Hadden MK, Lubbers DJ, Blagg BS.
Geldanamycin, radicicol, and chimeric inhibitors of the Hsp90 N-terminal ATP binding site.
Curr Top Med Chem. 2006;6(11):1173-82. Review. PMID: 16842154
- Katayama DS, Nayar R, Chou DK, Valente JJ, Cooper J, Henry CS, Vander Velde DG, Villarete L, Liu CP, Manning MC.
Effect of buffer species on the thermally induced aggregation of interferon-tau.
J Pharm Sci. 2006 Jun;95(6):1212-26. PMID: 16637050
- Liederer BM, Borchardt RT.
Enzymes involved in the bioconversion of ester-based prodrugs.
J Pharm Sci. 2006 Jun;95(6):1177-95. Review. PMID: 16639719
- Sarthy J, Gamblin TC.
A light scattering assay for arachidonic acid-induced tau fibrillization without interfering micellization.
Anal Biochem. 2006 Jun 1;353(1):150-2. Epub 2006 Mar 29. PMID: 16620751
- Wang M, Unruh JR, Johnson CK, Kuczera K, Schowen RL, Borchardt RT.
Effects of ligand binding and oxidation on hinge-bending motions in S-adenosyl-L-homocysteine hydrolase.
Biochemistry. 2006 Jun 27;45(25):7778-86. PMID: 16784229
- Xiong H, Chen XW.
Kernel-based distance metric learning for microarray data classification.
BMC Bioinformatics. 2006 Jun 14;7:299. PMID: 16774678
- Xu S, Ying J, Jiang B, Guo W, Adachi T, Sharov V, Lazar H, Menzoian J, Knyushko TV, Bigelow D, Schöneich C, Cohen RA.
Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.
Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2220-7. Epub 2006 Jan 6. PMID: 16399855
- Ye QZ, Xie SX, Ma ZQ, Huang M, Hanzlik RP.
Structural basis of catalysis by monometalated methionine aminopeptidase.
Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9470-5. Epub 2006 Jun 12. PMID: 16769889
- Zhang L, Wang Y, Picking WL, Picking WD, De Guzman RN.
Solution structure of monomeric BsaL, the type III secretion needle protein of Burkholderia pseudomallei.
J Mol Biol. 2006 Jun 2;359(2):322-30. Epub 2006 Mar 30. PMID: 16631790

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May 2006

- Johnson MA, Rajan V, Miller CE, Wightman RM.
Dopamine release is severely compromised in the R6/2 mouse model of Huntington's disease. J Neurochem. 2006 May;97(3):737-46. Epub 2006 Mar 29. PMID: 16573654
- Midwinter RG, Cheah FC, Moskovitz J, Vissers MC, Winterbourn CC.
IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation. Biochem J. 2006 May 15;396(1):71-8. PMID: 16405428
- Wang M, Shen G, Blagg BS.
Radanamycin, a macrocyclic chimera of radicicol and geldanamycin. Bioorg Med Chem Lett. 2006 May 1;16(9):2459-62. Epub 2006 Feb 7. PMID: 16464590
- Zabell KM, Laurence JS, Kinch MS, Knapp DW, Stauffacher CV.
Expression and purification of the intact cytoplasmic domain of the human ephrin receptor A2 tyrosine kinase in Escherichia coli. Protein Expr Purif. 2006 May;47(1):210-6. Epub 2005 Dec 20. PMID: 16426859

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April 2006

- Floor E, Maples AM, Rankin CA, Yaganti VM, Shank SS, Nichols GS, O'Laughlin M, Galeva NA, Williams TD.
A one-carbon modification of protein lysine associated with elevated oxidative stress in human substantia nigra.
J Neurochem. 2006 Apr;97(2):504-14. Epub 2006 Mar 15. PMID: 16539661
- Frankenfeld CN, Rosenbaugh MR, Fogarty BA, Lunte SM.
Separation and detection of peroxynitrite and its metabolites by capillary electrophoresis with UV detection.
J Chromatogr A. 2006 Apr 14;1111(2):147-52. Epub 2005 Jun 13. PMID: 16569573
- Goebel S, Huang M, Davis WC, Jennings M, Siahaan TJ, Alexander JS, Kevil CG.
VEGF-A stimulation of leukocyte adhesion to colonic microvascular endothelium: implications for inflammatory bowel disease.
Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G648-54. Epub 2005 Nov 17. PMID: 16293653
- Hanbauer I, Moskovitz J.
The yeast cytosolic thioredoxins are involved in the regulation of methionine sulfoxide reductase A.
Free Radic Biol Med. 2006 Apr 15;40(8):1391-6. Epub 2006 Jan 13. PMID: 16631529
- Jiang H, Timmermann BN, Gang DR.
Use of liquid chromatography-electrospray ionization tandem mass spectrometry to identify diarylheptanoids in turmeric (Curcuma longa L.) rhizome.
J Chromatogr A. 2006 Apr 7;1111(1):21-31. Epub 2006 Feb 21. PMID: 16490201
- Kobayashi N, Ikesue A, Majumdar S, Siahaan TJ.
Inhibition of e-cadherin-mediated homotypic adhesion of Caco-2 cells: a novel evaluation assay for peptide activities in modulating cell-cell adhesion.
J Pharmacol Exp Ther. 2006 Apr;317(1):309-16. Epub 2005 Dec 21. PMID: 16371447
- Sharov VS, Galeva NA, Kanski J, Williams TD, Schöneich C.
Age-associated tyrosine nitration of rat skeletal muscle glycogen phosphorylase b: characterization by HPLC-nanoelectrospray-tandem mass spectrometry.
Exp Gerontol. 2006 Apr;41(4):407-16. Epub 2006 Apr 17. PMID: 16616821
- Waetzig JD, Hanson PR.
Temporary phosphate tethers: a metathesis strategy to differentiated polyol subunits.
Org Lett. 2006 Apr 13;8(8):1673-6. PMID: 16597138
- Xie SX, Huang WJ, Ma ZQ, Huang M, Hanzlik RP, Ye QZ.
Structural analysis of metalloform-selective inhibition of methionine aminopeptidase.
Acta Crystallogr D Biol Crystallogr. 2006 Apr;62(Pt 4):425-32. Epub 2006 Mar 18. PMID: 16552144
- Young AM, Audus KL, Proudfoot J, Yazdanian M.
Tetrazole compounds: the effect of structure and pH on Caco-2 cell permeability.
J Pharm Sci. 2006 Apr;95(4):717-25. PMID: 16498570.

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March 2006

- Balakrishna R, Wood SJ, Nguyen TB, Miller KA, Suresh Kumar EV, Datta A, David SA.
Structural correlates of antibacterial and membrane-permeabilizing activities in acylpolyamines.
Antimicrob Agents Chemother. 2006 Mar;50(3):852-61. PMID: 16495242
- Blackman B, Georg GI, Lushington GH.
CoMSIA/QSAR Models for Vacuolar (H+) ATPase Inhibition by Selected Benzoate and Benzolactone Species.
Lett. Drug Des. Disc. 2006 Mar;3(2):104-107.
- Cerny MA, Hanzlik RP.
Cytochrome P450-catalyzed oxidation of N-benzyl-N-cyclopropylamine generates both cyclopropanone hydrate and 3-hydroxypropionaldehyde via hydrogen abstraction, not single electron transfer.
J Am Chem Soc. 2006 Mar 15;128(10):3346-54. PMID: 16522116
- Chen J, Im W, Brooks CL 3rd.
Balancing solvation and intramolecular interactions: toward a consistent generalized Born force field.
J Am Chem Soc. 2006 Mar 22;128(11):3728-36. PMID: 16536547
- Darboe N, Kenjale R, Picking WL, Picking WD, Middaugh CR.
Physical characterization of MxiH and PrgI, the needle component of the type III secretion apparatus from Shigella and Salmonella.
Protein Sci. 2006 Mar;15(3):543-52. PMID: 16501225
- Deane JE, Cordes FS, Roversi P, Johnson S, Kenjale R, Picking WD, Picking WL, Lea SM, Blocker A.
Expression, purification, crystallization and preliminary crystallographic analysis of MxiH, a subunit of the Shigella flexneri type III secretion system needle.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Mar 1;62(Pt 3):302-5. Epub 2006 Feb 28. PMID: 16511329
- Fang J, Dong Y, Lushington GH, Ye QZ, Georg GI.
Support vector machines in HTS data mining: Type I MetAPs inhibition study.
J Biomol Screen. 2006 Mar;11(2):138-44. Epub 2006 Jan 17. PMID: 16418315
- Fogarty BA, Lacher NA, Lunte SM.
Microchip capillary electrophoresis: application to peptide analysis.
Methods Mol Biol. 2006;339:159-86. Review. PMID: 16790873
- Funk JL, Oyarzo JN, Frye JB, Chen G, Lantz RC, Jolad SD, Sólyom AM, Timmermann BN.
Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis.
J Nat Prod. 2006 Mar;69(3):351-5. PMID: 16562833
- Gu JQ, Wang Y, Franzblau SG, Montenegro G, Timmermann BN.
Dereplication of pentacyclic triterpenoids in plants by GC-EI/MS.
Phytochem Anal. 2006 Mar;17(2):102-6. PMID: 16634286
- Jiang H, Somogyi A, Jacobsen NE, Timmermann BN, Gang DR.
Analysis of curcuminoids by positive and negative electrospray ionization and tandem mass spectrometry.
Rapid Commun Mass Spectrom. 2006 Mar 30;20(6):1001-12. PMID: 16479557
- Khownium K, Wood SJ, Miller KA, Balakrishna R, Nguyen TB, Kimbrell MR, Georg GI, David SA.
Novel endotoxin-sequestering compounds with terephthalaldehyde-bis-guanylhydrazone scaffolds.
Bioorg Med Chem Lett. 2006 Mar 1;16(5):1305-8. Epub 2006 Jan 11. PMID: 16377188
- Li B, Schowen RL, Topp EM, Borchardt RT.
Effect of N-1 and N-2 residues on peptide deamidation rate in solution and solid state.
AAPS J. 2006 Mar 20;8(1):E166-73. PMID: 16584125
- Peng W, Blagg BS.
A versatile approach toward the ansamycin antibiotics.
Org Lett. 2006 Mar 2;8(5):975-8. PMID: 16494488
- Sharov VS, Dremina ES, Galeva NA, Williams TD, Schöneich C.
Quantitative mapping of oxidation-sensitive cysteine residues in SERCA in vivo and in vitro by HPLC-electrospray-tandem MS: selective protein oxidation during biological aging.
Biochem J. 2006 Mar 15;394(Pt 3):605-15. PMID: 16307534
- Yasuji T, Haslam J, Kajiyama A, McIntosh MP, Rajewski RA.
Preliminary evaluation of polymer-based drug composite microparticle production by coacervate desolvation with supercritical carbon dioxide.
J Pharm Sci. 2006 Mar;95(3):581-8. PMID: 16419052

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February 2006

- Avila C, Kornilayev BA, Blagg BS.
Development and optimization of a useful assay for determining Hsp90's inherent ATPase activity.
Bioorg Med Chem. 2006 Feb 15;14(4):1134-42. Epub 2005 Oct 4. PMID: 16213144
-Burns MR, Jenkins SA, Wood SJ, Miller K, David SA.
Structure-activity relationships in lipopolysaccharide neutralizers: design, synthesis, and biological evaluation of a 540-membered amphipathic bisamide library.
J Comb Chem. 2006 Jan-Feb;8(1):32-43.
- De Guzman RN, Goto NK, Dyson HJ, Wright PE.
Structural basis for cooperative transcription factor binding to the CBP coactivator.
J Mol Biol. 2006 Feb 3;355(5):1005-13. Epub 2005 Oct 5. PMID: 16253272
-Guo JX, Wood SJ, David SA, Lushington GH.
Molecular modeling analysis of the interaction of novel bis-cationic ligands with the lipid A moiety of lipopolysaccharide.
Bioorg Med Chem Lett. 2006 Feb;16(3):714-7. Epub 2005 Nov 2.
- Guo JX, Wu JJ, Wright JB, Lushington GH.
Mechanistic insight into acetylcholinesterase inhibition and acute toxicity of organophosphorus compounds: a molecular modeling study.
Chem Res Toxicol. 2006 Feb;19(2):209-16. PMID: 16485896
- Li MW, Huynh BH, Hulvey MK, Lunte SM, Martin RS.
Design and characterization of poly(dimethylsiloxane)-based valves for interfacing continuous-flow sampling to microchip electrophoresis.
Anal Chem. 2006 Feb 15;78(4):1042-51. PMID: 16478094
- Liederer BM, Fuchs T, Vander Velde D, Siahaan TJ, Borchardt RT.
Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.
J Med Chem. 2006 Feb 23;49(4):1261-70. PMID: 16480263
-Lushington GH.
Computational approaches in medicinal chemistry: surveys, case studies and future directions.
Curr Top Med Chem. 2006;6(1):1.
-Lushington GH, Guo JX, Hurley MM.
Acetylcholinesterase: molecular modeling with the whole toolkit.
Curr Top Med Chem. 2006;6(1):57-73.
- Malinakova HC.
Synthetic Applications of Multi-component Coupling Reactions Proceeding via Bis-p-allylpalladium Complexes.
Lett. Org. Chem. 2006 Feb;3(2):82-90.
-Nelson BN, Schieber LJ, Barich DH, Lubach JW, Offerdahl TJ, Lewis DH, Heinrich JP, Munson EJ.
Multiple-sample probe for solid-state NMR studies of pharmaceuticals.
Solid State Nucl Magn Reson. 2006 Feb;29(1-3):204-13. Epub 2005 Oct 24.
- Schonhoff CM, Matsuoka M, Tummala H, Johnson MA, Estevéz AG, Wu R, Kamaid A, Ricart KC, Hashimoto Y, Gaston B, Macdonald TL, Xu Z, Mannick JB.
S-nitrosothiol depletion in amyotrophic lateral sclerosis.
Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2404-9. Epub 2006 Feb 6. PMID: 16461917
- Seyb KI, Ansar S, Bean J, Michaelis ML.
beta-Amyloid and endoplasmic reticulum stress responses in primary neurons: effects of drugs that interact with the cytoskeleton.
J Mol Neurosci. 2006;28(2):111-23. PMID: 16679552
- Shakir MA, Gill JS, Lundquist EA.
Interactions of UNC-34 Enabled with Rac GTPases and the NIK kinase MIG-15 in Caenorhabditis elegans axon pathfinding and neuronal migration.
Genetics. 2006 Feb;172(2):893-913. Epub 2005 Oct 3. PMID: 16204220, PMCID: PMC1456253
-Spletstoser JT, Turunen BJ, Desino K, Rice A, Datta A, Dutta D, Huff JK, Himes RH, Audus KL, Seelig A, Georg GI.
Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells.
Bioorg Med Chem Lett. 2006 Feb;16(3):495-8. Epub 2005 Nov 10.

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January 2006

-Clavreul N, Adachi T, Pimental DR, Ido Y, Schoneich C, Cohen RA.
S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.
FASEB J. 2006 Jan 13; [Epub ahead of print]
-Pinto CS, Seifert R.
Decreased GTP-stimulated adenylyl cyclase activity in HPRT-deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes.
J Neurochem. 2006 Jan;96(2):454-9. Epub 2005 Dec 8.
-Borchardt RT.
Editorial.
J Pharm Sci. 2006 Jan 12;95(3):471 [Epub ahead of print]
-Borchardt RT.
Editorial.
J Pharm Sci. 2006 Jan;95(1):1.
-Borchardt RT.
Editorial.
J Pharm Sci. 2006 Jan;95(1):2.
-Borchardt RT.
Editorial.
J Pharm Sci. 2006 Jan;95(1):3.
-Dremina ES, Sharov VS, Schoneich C.
Displacement of SERCA from SR Lipid Caveolae-Related Domains by Bcl-2: A Possible Mechanism for SERCA Inactivation.
Biochemistry. 2006 Jan 10;45(1):175-84.
-Ge H, Vasandani V, Huff JK, Audus KL, Himes RH, Seelig A, Georg GI.
Synthesis and interactions of 7-deoxy-, 10-deacetoxy, and 10-deacetoxy-7-deoxypaclitaxel with NCI/ADR-RES cancer cells and bovine brain microvessel endothelial cells.
Bioorg Med Chem Lett. 2006 Jan 15;16(2):433-6. Epub 2005 Nov 3.
-Hershberger JC, Zhang L, Lu G, Malinakova HC.
Polymer-supported palladacycles: efficient reagents for synthesis of benzopyrans with palladium recovery. Relationship among resin loading, Pd:P ratio, and reactivity of immobilized palladacycles.
J Org Chem. 2006 Jan 6;71(1):231-5.
-Xie SX, Ghorai P, Ye QZ, Buschauer A, Seifert R.
Probing ligand-specific histamine H1- and H2-receptor conformations with NG-acylated imidazolylpropylguanidines.
J Pharmacol Exp Ther. 2006 Jan 4; [Epub ahead of print]
-Harrington A, Darboe N, Kenjale R, Picking WL, Middaugh CR, Birket S, Picking WD.
Characterization of the Interaction of Single Tryptophan Containing Mutants of IpaC from Shigella flexneri with Phospholipid Membranes.
Biochemistry. 2006 Jan 17;45(2):626-36.
-Huang M, Xie SX, Ma ZQ, Hanzlik RP, Ye QZ.
Metal mediated inhibition of methionine aminopeptidase by quinolinyl sulfonamides.
Biochem Biophys Res Commun. 2006 Jan 13;339(2):506-13. Epub 2005 Nov 15.
-Wood SJ, Miller KA, Lushington GH, Burns MR, David SA.
Anti-endotoxin agents. 3. Rapid identification of high-affinity lipopolysaccharide-binding compounds in a substituted polyamine library.
Comb Chem High Throughput Screen. 2006 Jan;9(1):27-36.
-Li Q, Hanzlik RP, Weaver RF, Schonbrunn E.
Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core(,).
Biochemistry. 2006 Jan 24;45(3):701-8.
- Lushington GH, Guo JX, Hurley MM.
Acetylcholinesterase: molecular modeling with the whole toolkit.
Curr Top Med Chem. 2006;6(1):57-73. Review. PMID: 16454758
-Geller DA, Tsung A, Marsh JW, Dvorchik I, Gamblin TC, Carr BI.
Outcome of 1000 Liver Cancer Patients Evaluated at the UPMC Liver Cancer Center.
J Gastrointest Surg. 2006 Jan;10(1):63-8.
-Okere IC, Chandler MP, McElfresh T, Rennison J, Sharov V, Sabbah HN, Tserng KY, Hoit BD, Ernsberger P, Young ME, Stanley WC.
Differential Effects of Saturated and Unsaturated Fatty Acid Diets on Cardiomyocyte Apoptosis, Adipose Distribution, and Serum Leptin.
Am J Physiol Heart Circ Physiol. 2006 Jan 27; [Epub ahead of print]
-Tian F, Sane S, Rytting JH.
Calorimetric investigation of protein/amino acid interactions in the solid state.
Int J Pharm. 2006 Jan 18; [Epub ahead of print]

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December 2005

- Gamblin TC, Geller DA.
Downstaging hepatocellular carcinoma prior to liver transplantation.
Liver Transpl. 2005 Dec;11(12):1466-8.
-Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL.
Mode of Binding of Methyl Acceptor Substrates to the Adrenaline-Synthesizing Enzyme Phenylethanolamine N-Methyltransferase: Implications for Catalysis.
Biochemistry. 2005 Dec 27;44(51):16875-16885.
-Blagg BS, Kerr TD.
Hsp90 inhibitors: Small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation.
Med Res Rev. 2005 Dec 29; [Epub ahead of print]
-Chen XW, Liu M.
Prediction of protein-protein interactions using random decision forest framework.
Bioinformatics. 2005 Dec 15;21(24):4394-400. Epub 2005 Oct 18.
-Grunewald GL, Lu J, Criscione KR, Okoro CO.
Inhibitors of phenylethanolamine N-methyltransferase devoid of alpha2-adrenoceptor affinity.
Bioorg Med Chem Lett. 2005 Dec 1;15(23):5319-23. Epub 2005 Sep 19.
-Gifford R, Kehoe JJ, Barnes SL, Kornilayev BA, Alterman MA, Wilson GS.
Protein interactions with subcutaneously implanted biosensors.
Biomaterials. 2005 Dec 15; [Epub ahead of print]
-Iyengar R, Schildknegt K, Morton M, Aube J.
Revisiting a classic approach to the Aspidosperma alkaloids: an intramolecular Schmidt reaction mediated synthesis of (+)-aspidospermidine.
J Org Chem. 2005 Dec 23;70(26):10645-52.
-Hurley MM, Balboa A, Lushington GH, Guo J.
Interactions of organophosphorus and related compounds with cholinesterases, a theoretical study.
Chem Biol Interact. 2005 Dec 15;157-158:321-5. Epub 2005 Nov 9.
-Kenjale R, Wilson J, Zenk SF, Saurya S, Picking WL, Picking WD, Blocker A.
The needle component of the type III secreton of Shigella regulates the activity of the secretion apparatus.
J Biol Chem. 2005 Dec 30;280(52):42929-37. Epub 2005 Oct 14.
-Lushington GH, Zaidi A, Michaelis ML.
Theoretically predicted structures of plasma membrane Ca(2+)-ATPase and their susceptibilities to oxidation.
J Mol Graph Model. 2005 Dec;24(3):175-85. Epub 2005 Sep 19.
-Liederer BM, Phan KT, Ouyang H, Borchardt RT.
Significant differences in the disposition of cyclic prodrugs of opioid peptides in rats and guinea pigs following IV administration.
J Pharm Sci. 2005 Dec;94(12):2676-87.
-Krogmeier SL, Reddy DS, Vander Velde D, Lushington GH, Siahaan TJ, Middaugh CR, Borchardt RT, Topp EM.
Deamidation of model beta-turn cyclic peptides in the solid state.
J Pharm Sci. 2005 Dec;94(12):2616-31.
-Offerdahl TJ, Salsbury JS, Dong Z, Grant DJ, Schroeder SA, Prakash I, Gorman EM, Barich DH, Munson EJ.
Quantitation of crystalline and amorphous forms of anhydrous neotame using 13C CPMAS NMR spectroscopy
J Pharm Sci. 2005 Dec;94(12):2591-605.
-Petersson J, Rohdin M, Sanchez-Crespo A, Nyren S, Jacobsson H, Larsson SA, Lindahl SG, Linnarsson D, Glenny RW, Mure M.
Paradoxical redistribution of pulmonary blood flow in prone and supine humans exposed to hypergravity.
J Appl Physiol. 2006 Jan;100(1):240-8. Epub 2005 Sep 8.
-Gille A, Guo J, Mou TC, Doughty MB, Lushington GH, Seifert R.
Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.
Biochem Pharmacol. 2005 Dec 19;71(1-2):89-97. Epub 2005 Nov 4.
-Tremblay JM, Unruh JR, Johnson CK, Yarbrough LR.
Mechanism of interaction of PITPalpha with membranes: conformational changes in the C-terminus associated with membrane binding.
Arch Biochem Biophys. 2005 Dec 15;444(2):112-20. Epub 2005 Nov 15.
-Shakir MA, Lundquist EA.
Analysis of Cell Migration in Caenorhabditis elegans.
Methods Mol Biol. 2005;294:159-73.
-Kanski J, Schoneich C.
Protein nitration in biological aging: proteomic and tandem mass spectrometric characterization of nitrated sites. Methods Enzymol. 2005;396:160-71.

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November 2005

-Wrobel G, Seifert R, Ingebrandt S, Enderlein J, Ecken H, Baumann A, Kaupp UB, Offenhausser A.
Cell-transistor coupling: investigation of potassium currents recorded with p- and n-channel FETs.
Biophys J. 2005 Nov;89(5):3628-38. Epub 2005 Aug 12.
-Wu Q, Gee CL, Lin F, Tyndall JD, Martin JL, Grunewald GL, McLeish MJ.
Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase.
J Med Chem. 2005 Nov 17;48(23):7243-52.
-Tongiani S, Velde DV, Ozeki T, Stella VJ.
Sulfoalkyl ether-alkyl ether cyclodextrin derivatives, their synthesis, NMR characterization, and binding of 6alpha-methylprednisolone.
J Pharm Sci. 2005 Nov;94(11):2380-92.
-Fang J, Haasl RJ, Dong Y, Lushington GH.
Discover protein sequence signatures from protein-protein interaction data.
BMC Bioinformatics. 2005 Nov 23;6:277.
-Yue W, Koen YM, Williams TD, Hanzlik RP.
Use of isotopic signatures for mass spectral detection of protein adduction by chemically reactive metabolites of bromobenzene: studies with model proteins.
Chem Res Toxicol. 2005 Nov;18(11):1748-54.
-Sharov VS, Dremina ES, Galeva NA, Williams TD, Schoneich C.
Quantitative mapping of oxidation-sensitive cysteine residues in SERCA in vivo and in vitro by HPLC-electrospray-tandem mass spectrometry: selective protein oxidation during biological aging.
Biochem J. 2005 Nov 25; [Epub ahead of print]
-Cordes FS, Daniell S, Kenjale R, Saurya S, Picking WL, Picking WD, Booy F, Lea SM, Blocker A.
Helical packing of needles from functionally altered Shigella type III secretion systems.
J Mol Biol. 2005 Nov 25;354(2):206-11. Epub 2005 Oct 7.
-Zeng X, Chen XW.
SMO-based pruning methods for sparse least squares support vector machines.
IEEE Trans Neural Netw. 2005 Nov;16(6):1541-6.
-Gamblin TC, Wall CE Jr, Royer GM, Dalton ML, Ashley DW.
Delayed splenic rupture: case reports and review of the literature.
J Trauma. 2005 Nov;59(5):1231-4. No abstract available.
-Zhang Y, Go EP, Jiang H, Desaire H.
A novel mass spectrometric method to distinguish isobaric monosaccharides that are phosphorylated or sulfated using ion-pairing reagents.
J Am Soc Mass Spectrom. 2005 Nov;16(11):1827-39. Epub 2005 Sep 26.
-Zeng Y, Aube J.
An expeditious total synthesis of (+/-)-stenine.
J Am Chem Soc. 2005 Nov 16;127(45):15712-3.

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October 2005

-Agbas A, Zaidi A, Michaelis EK.
Decreased activity and increased aggregation of brain calcineurin during aging.
Brain Res. 2005 Oct 12;1059(1):59-71. Epub 2005 Sep 8.
-Kang SO, Powell D, Bowman-James K.
Anion binding motifs: topicity and charge in amidocryptands.
J Am Chem Soc. 2005 Oct 5;127(39):13478-9.
-Liederer BM, Borchardt RT.
Stability of oxymethyl-modified coumarinic acid cyclic prodrugs of diastereomeric opioid peptides in biological media from various animal species including human.
J Pharm Sci. 2005 Oct;94(10):2198-206.
-Treude T, Knittel K, Blumenberg M, Seifert R, Boetius A.
Subsurface microbial methanotrophic mats in the Black Sea.
Appl Environ Microbiol. 2005 Oct;71(10):6375-8.
-Rayabarapu DK, Tunge JA.
Catalytic decarboxylative sp-sp3 coupling.
J Am Chem Soc. 2005 Oct 5;127(39):13510-1.
-Yi L, Bandu ML, Desaire H.
Identifying lactone hydrolysis in pharmaceuticals. A tool for metabolite structural characterization.
Anal Chem. 2005 Oct 15;77(20):6655-63.
-Wang X, Pal R, Chen XW, Limpeanchob N, Kumar KN, Michaelis EK.
High intrinsic oxidative stress may underlie selective vulnerability of the hippocampal CA1 region
Brain Res Mol Brain Res. 2005 October 31;140(1-2):120-6. Epub 2005 Aug 31.
-Knyushko TV, Sharov VS, Williams TD, Schoneich C, Bigelow DJ.
3-Nitrotyrosine modification of SERCA2a in the aging heart: a distinct signature of the cellular redox environment.
Biochemistry. 2005 Oct 4;44(39):13071-81.
-Beck ZQ, Aldrich CC, Magarvey NA, Georg GI, Sherman DH.
Chemoenzymatic Synthesis of Cryptophycin/Arenastatin Natural Products.
Biochemistry. 2005 Oct 18;44(41):13457-13466.

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September 2005

-Cohen RS.
Microtubule motors: LSD2 trips the toggle.
Curr Biol. 2005 Sep 6;15(17):R651-3.
-Alterman MA, Kornilayev B, Duzhak T, Yakovlev D.
Quantitative analysis of cytochrome p450 isozymes by means of unique isozyme-specific tryptic peptides: a proteomic approach.
Drug Metab Dispos. 2005 Sep;33(9):1399-407. Epub 2005 Jun 10.
-Bandu ML, Wilson J, Vachet RW, Dalpathado DS, Desaire H.
STEP (Statistical Test of Equivalent Pathways) analysis: a mass spectrometric method for carbohydrates and peptides.
Anal Chem. 2005 Sep 15;77(18):5886-93.
-Yu XM, Shen G, Neckers L, Blake H, Holzbeierlein J, Cronk B, Blagg BS.
Hsp90 inhibitors identified from a library of novobiocin analogues.
J Am Chem Soc. 2005 Sep 21;127(37):12778-9.
-Timberlake GT, Yousef AL, Chiles SR, Moses RA, Givens RS.
Bonding corneal tissue: applications of photoactivated diazopyruvoyl cross-linking agent.
Photochem Photobiol. 2005 Sep-Oct;81(5):1180-5.
-Haack T, Haack K, Diederich WE, Blackman B, Roy S, Pusuluri S, Georg GI.
Formal total syntheses of the (-)-salicylihalamides A and B from D-glucose and L-rhamnose.
J Org Chem. 2005 Sep 16;70(19):7592-604.
-Judson PN, Cooke PA, Doerrer NG, Greene N, Hanzlik RP, Hardy C, Hartmann A, Hinchliffe D, Holder J, Muller L, Steger-Hartmann T, Rothfuss A, Smith M, Thomas K, Vessey JD, Zeiger E.
Towards the creation of an international toxicology information centre.
Toxicology. 2005 Sep 15;213(1-2):117-28.
-Yu XM, Shen G, Neckers L, Blake H, Holzbeierlein J, Cronk B, Blagg BS.
Hsp90 inhibitors identified from a library of novobiocin analogues.
J Am Chem Soc. 2005 Sep 21;127(37):12778-9.
-Zhou J, Zhang H, Cohen RS, Pandey SC.
Effects of estrogen treatment on expression of brain-derived neurotrophic factor and cAMP response element-binding protein expression and phosphorylation in rat amygdaloid and hippocampal structures.
Neuroendocrinology. 2005;81(5):294-310. Epub 2005 Sep 21.
-Foland TB, Dentler WL, Suprenant KA, Gupta ML Jr, Himes RH.
Paclitaxel-induced microtubule stabilization causes mitotic block and apoptotic-like cell death in a paclitaxel-sensitive strain of Saccharomyces cerevisiae.
Yeast. 2005 Sep;22(12):971-8.

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August 2005

-Blumenberg M, Seifert R, Nauhaus K, Pape T, Michaelis W.
In vitro study of lipid biosynthesis in an anaerobically methane-oxidizing microbial mat.
Appl Environ Microbiol. 2005 Aug;71(8):4345-51.
-Hopkins CD, Guan L, Malinakova HC.
Regiocontrolled, palladium-catalyzed bisfunctionalization of allenyl esters. Multicomponent coupling approaches to highly substituted alpha,beta-unsaturated delta-lactones.
J Org Chem. 2005 Aug 19;70(17):6848-62.
-Li B, O'Meara MH, Lubach JW, Schowen RL, Topp EM, Munson EJ, Borchardt RT.
Effects of sucrose and mannitol on asparagine deamidation rates of model peptides in solution and in the solid state.
J Pharm Sci. 2005 Aug;94(8):1723-35.
-MacDougall C, Powell JP, Johnson CK, Edmond MB, Polk RE.
Hospital and community fluoroquinolone use and resistance in Staphylococcus aureus and Escherichia coli in 17 US hospitals.
Clin Infect Dis. 2005 Aug 15;41(4):435-40. Epub 2005 Jun 28.
-Osborn KD, Zaidi A, Urbauer RJ, Michaelis ML, Johnson CK.
Single-molecule characterization of the dynamics of calmodulin bound to oxidatively modified plasma-membrane Ca2+-ATPase.
Biochemistry. 2005 Aug 23;44(33):11074-81.
-Li K, Zeng Y, Neuenswander B, Tunge JA.
Sequential Pd(II)-Pd(0) catalysis for the rapid synthesis of coumarins.
J Org Chem. 2005 Aug 5;70(16):6515-8.
-MacDougall C, Harpe SE, Powell JP, Johnson CK, Edmond MB, Polk RE.
Pseudomonas aeruginosa, Staphylococcus aureus, and fluoroquinolone use.
Emerg Infect Dis. 2005 Aug;11(8):1197-204.
-Slaughter BD, Unruh JR, Price ES, Huynh JL, Bieber Urbauer RJ, Johnson CK.
Sampling unfolding intermediates in calmodulin by single-molecule spectroscopy.
J Am Chem Soc. 2005 Aug 31;127(34):12107-14.
-Bowman-James K.
Alfred Werner revisited: the coordination chemistry of anions.
Acc Chem Res. 2005 Aug;38(8):671-8. Review.
-Yu C, Alterman M, Dobrowsky RT.
Ceramide displaces cholesterol from lipid rafts and decreases the association of the cholesterol binding protein caveolin-1.
J Lipid Res. 2005 Aug;46(8):1678-91. Epub 2005 May 1.

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July 2005

-Cohen RS, Zhang S, Dollar GL.
The positional, structural, and sequence requirements of the Drosophila TLS RNA localization element.
RNA. 2005 Jul;11(7):1017-29.
-Rankin CA, Sun Q, Gamblin TC.
Pseudo-phosphorylation of tau at Ser202 and Thr205 affects tau filament formation.
Brain Res Mol Brain Res. 2005 Jul 29;138(1):84-93.
-Simeonov M, Altuve A, Massiah MA, Wang A, Eastman MA, Benson DR, Rivera M.
Mitochondrial and microsomal ferric b5 cytochromes exhibit divergent conformational plasticity in the context of a common fold. Biochemistry.
2005 Jul 5;44(26):9308-19.
-Yu XM, Han H, Blagg BS.
Synthesis of mono- and dihydroxylated furanoses, pyranoses, and an oxepanose for the preparation of natural product analogue libraries.
J Org Chem. 2005 Jul 8;70(14):5599-605.
-Nauser T, Casi G, Koppenol WH, Schoneich C.
Intramolecular addition of cysteine thiyl radicals to phenylalanine in peptides: formation of cyclohexadienyl type radicals.
Chem Commun (Camb). 2005 Jul 21;(27):3400-2. Epub 2005 Jun 9.
-Grecian S, Wrobleski AD, Aube J.
Regioselective single and double conjugate additions to substituted cyclohexa-2,5-dienone monoacetals.
Org Lett. 2005 Jul 21;7(15):3167-70.
-Li W, Liu H, Scott EE, Grater F, Halpert JR, Luo X, Shen J, Jiang H.
Possible pathway(s) of testosterone egress from the active site of cytochrome P450 2B1: a steered molecular dynamics simulation.
Drug Metab Dispos. 2005 Jul;33(7):910-9. Epub 2005 Apr 8.
-Ding X, Staudinger JL.
The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
J Pharmacol Exp Ther. 2005 Jul;314(1):120-7. Epub 2005 Apr 15.

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June 2005

-Dremina ES, Sharov VS, Schoneich C.
Protein tyrosine nitration in rat brain is associated with raft proteins, flotillin-1 and alpha-tubulin: effect of biological aging.
J Neurochem. 2005 Jun;93(5):1262-71.
-Yang Y, Lundquist EA.
The actin-binding protein UNC-115/abLIM controls formation of lamellipodia and filopodia and neuronal morphogenesis in Caenorhabditis elegans.
Mol Cell Biol. 2005 Jun;25(12):5158-70.
-Yu J, Chen XW.
Bayesian neural network approaches to ovarian cancer identification from high-resolution mass spectrometry data. Bioinformatics.
2005 Jun 1;21 Suppl 1:i487-i494.
-Burger EC, Tunge JA.
Ruthenium-catalyzed stereospecific decarboxylative allylation of non-stabilized ketone enolates.
Chem Commun (Camb). 2005 Jun 14;(22):2835-7. Epub 2005 Apr 21.
-Pinto CS, Jinnah HA, Shirley TL, Nyhan WL, Seifert R.
Altered membrane NTPase activity in Lesch-Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT-deficient cell lines.
J Neurochem. 2005 Jun;93(6):1579-86.
-Hanzlik RP, Fowler SC, Fisher DH.
Relative bioavailability of calcium from calcium formate, calcium citrate, and calcium carbonate.
J Pharmacol Exp Ther. 2005 Jun;313(3):1217-22. Epub 2005 Feb 25.
-Fogarty BA, Heppert KE, Cory TJ, Hulbutta KR, Martin RS, Lunte SM.
Rapid fabrication of poly(dimethylsiloxane)-based microchip capillary electrophoresis devices using CO2 laser ablation.
Analyst. 2005 Jun;130(6):924-30. Epub 2005 Apr 25.
-Kanski J, Hong SJ, Schoneich C.
Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass spectrometry.
J Biol Chem. 2005 Jun 24;280(25):24261-6. Epub 2005 Apr 25.
-Gee CL, Nourse A, Hsin AY, Wu Q, Tyndall JD, Grunewald GL, McLeish MJ, Martin JL.
Disulfide-linked dimers of human adrenaline synthesizing enzyme PNMT are catalytically active.
Biochim Biophys Acta. 2005 Jun 15;1750(1):82-92. Epub 2005 Apr 2.
-Gamblin TC, Nobles-James C, Bradley RA, Katner HP, Dale PS.
Cat scratch disease presenting as breast mastitis.
Can J Surg. 2005 Jun;48(3):254-5.
-Zeng Y, Li Q, Hanzlik RP, Aube J.
Synthesis of a small library of diketopiperazines as potential inhibitors of calpain.
Bioorg Med Chem Lett. 2005 Jun 15;15(12):3034-8.

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May 2005

-Calcagno AM, Fostel JM, Orchekowski RP, Alston JT, Mattes WB, Siahaan TJ, Ware JA.
Modulation of cell adhesion molecules in various epithelial cell lines after treatment with PP2.
Mol Pharm. 2005 May-Jun;2(3):170-84.
-Rodriguez AJ, Seipel SA, Hamill DR, Romancino DP, DI Carlo M, Suprenant KA, Bonder EM.
Seawi--a sea urchin piwi/argonaute family member is a component of MT-RNP complexes.
RNA. 2005 May;11(5):646-56.
-Shen G, Blagg BS.
Radester, a novel inhibitor of the Hsp90 protein folding machinery.
Org Lett. 2005 May 26;7(11):2157-60.
-Unruh JR, Gokulrangan G, Lushington GH, Johnson CK, Wilson GS.
Orientational dynamics and dye-DNA interactions in a dye-labeled DNA aptamer.
Biophys J. 2005 May;88(5):3455-65. Epub 2005 Feb 24.
-Yu JS, Ongarello S, Fiedler R, Chen XW, Toffolo G, Cobelli C, Trajanoski Z.
Ovarian cancer identification based on dimensionality reduction for high-throughput mass spectrometry data. Bioinformatics.
2005 May 15;21(10):2200-9. Epub 2005 Mar 22.
-Wang C, Tunge JA.
Ruthenium-catalyzed decarboxylative insertion of electrophiles.
Org Lett. 2005 May 26;7(11):2137-9.
-Wang M, Borchardt RT, Schowen RL, Kuczera K.
Domain motions and the open-to-closed conformational transition of an enzyme: a normal mode analysis of S-adenosyl-L-homocysteine hydrolase.
Biochemistry. 2005 May 17;44(19):7228-39.
-Wang M, Zhang J, Andrei D, Kuczera K, Borchardt RT, Wnuk SF.
Are L-adenosine and its derivatives substrates for S-adenosyl-L-homocysteine hydrolase?
J Med Chem. 2005 May 19;48(10):3649-53.
-Sheth AR, Lubach JW, Munson EJ, Muller FX, Grant DJ.
Mechanochromism of piroxicam accompanied by intermolecular proton transfer probed by spectroscopic methods and solid-phase changes.
J Am Chem Soc. 2005 May 11;127(18):6641-51.
-Sibug-Aga R, Laird BB.
Structure of a soft-sphere fluid at a soft repulsive wall: a comparison of weighted density-functional theories. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 May;69(5 Pt 1):051502. Epub 2004 May 26.

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